Results 51 to 60 of about 3,792,423 (300)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

GÖKÇEADA’DA GÖÇLERİN NÜFUS GELİŞİMİ ve DEĞİŞİMİ ÜZERİNE ETKİLERİ

open access: yesCoğrafi Bilimler Dergisi, 2005
Gökçeada (Imbros) is the biggest island of Turkey in the northeast Aegean Sea. Throughout history, Gökçeada has been the island of immigrant. Gökçeada is the epitome of migration.
Selver ÖZÖZEN KAHRAMAN
doaj   +1 more source

Traffic-Sensitive Live Migration of Virtual Machines [PDF]

open access: yes2015 15th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing, 2015
In this paper we address the problem of network contention between the migration traffic and the Virtual Machine (VM) application traffic for the live migration of co-located Virtual Machines. When VMs are migrated with pre-copy, they run at the source host during the migration.
Umesh Deshpande, Kate Keahey
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Which migration, what development. Unsettling the edifice of migration and development [PDF]

open access: yes, 2007
Raghuram P. Which migration, what development. Unsettling the edifice of migration and development. COMCAD Arbeitspapiere - working papers, 28.
Raghuram, Parvati
core  

TSMC: A Novel Approach for Live Virtual Machine Migration

open access: yesJournal of Applied Mathematics, 2014
Cloud computing attracted more and more attention in recent years, and virtualization technology is the key point for deploying infrastructure services in cloud environment.
Jiaxing Song   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Cost-aware live migration of services in the cloud [PDF]

open access: yesProceedings of the 3rd Annual Haifa Experimental Systems Conference, 2010
Cloud computing is a paradigm in which dynamically scalable and often virtualized resources are provided as a service over the Internet. It is gaining popularity in a variety of domains such as web hosting, enterprise systems, and e-commerce sites.
David Breitgand, Gilad Kutiel, Danny Raz
openaire   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Transfer Cost of Virtual Machine Live Migration in Cloud Systems [PDF]

open access: yes, 2017
Virtualised frameworks typically form the foundations of Cloud systems, where Virtual Machine (VM) instances provide execution environments for a diverse range of applications and services.
Getov, Vladimir, Sliwko, L.
core  

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