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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2007
Herpes zoster is a neurocutaneous disease caused by the varicella‐zoster virus and is associated with significant morbidity and long‐term sequelae in older adults. Until recently, treatment options for these complications have been primarily targeted at disease state management and symptom relief.
Denise R, Kockler, Michelle W, McCarthy
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Herpes zoster is a neurocutaneous disease caused by the varicella‐zoster virus and is associated with significant morbidity and long‐term sequelae in older adults. Until recently, treatment options for these complications have been primarily targeted at disease state management and symptom relief.
Denise R, Kockler, Michelle W, McCarthy
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LIVE ATTENUATED VARICELLA VACCINE
Annual Review of Microbiology, 1996Varicella-zoster virus (VZV) is a ubiquitous human pathogen that causes varicella, commonly called chicken pox; establishes latency; and reactivates as herpes zoster, referred to as shingles. A live attenuated varicella vaccine, derived from the Oka strain of VZV has clinical efficacy for the prevention of varicella.
A M, Arvin, A A, Gershon
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1990
A live varicella vaccine has been developed, and its safety and immunogenicity have been established in normal children as well as in high-risk children.
M, Takahashi +4 more
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A live varicella vaccine has been developed, and its safety and immunogenicity have been established in normal children as well as in high-risk children.
M, Takahashi +4 more
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Live Attenuated Influenza Vaccine
2014Cold-adapted Ann Arbor based live attenuated influenza vaccine (LAIV) has been available in the USA since 2003. The vaccine is efficacious against influenza infection. Features of LAIV include: easy administration suitable for mass immunization, cross-reactivity to drifted strains for broader coverage, and establishment of herd immunity for control of ...
Hong, Jin, Kanta, Subbarao
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Influenza Vaccination with a Live Attenuated Vaccine
AJN, American Journal of Nursing, 2009Influenza is a highly contagious, acute respiratory illness with a long history of outbreaks dating back several centuries. Although immunization is an effective means of protection against influenza, vaccination rates have been suboptimal, especially among certain high-risk groups, including children and health care personnel.
Michele, Michael +4 more
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Non-live pentavalent vaccines after live measles vaccine may increase mortality
Vaccine, 2018Live measles vaccine (MV) may have beneficial off-target/non-specific effects (NSEs) reducing child mortality beyond prevention of measles infection. In contrast, the non-live pentavalent (Diphtheria-Tetanus-Pertussis-H. influenzae Type B-Hepatitis B) vaccine has no beneficial NSEs. The NSEs are strongest for the most recent vaccine. Hence, sequence of
Fisker, Ane Bærent, Thysen, Sanne Marie
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Live Attenuated Vaccine Vectors
International Journal of Technology Assessment in Health Care, 1994AbstractSeveral different live attenuated vaccine vectors currently are under development. These vaccines are composed of living viruses or bacteria that are innocuous to the host but can replicate in host tissues and induce immune responses. The genes encoding foreign antigens can be inserted into these vectors to produce multivalent vaccines that ...
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Live attenuated influenza vaccine
2008The development of the live, attenuated influenza vaccine (LAIV), based on the cold-adapted (ca), attenuated ca A/Ann Arbor/6/60 and ca B/Ann Arbor/1/66 backbones, has spanned several decades. The vaccine contains three vaccine strains, two attenuated influenza A strains and one attenuated influenza B strain; these vaccine strains are genetic ...
Harry Greenberg, George Kemble
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Recombinant live virus vaccines
Immunology Letters, 1987Many successful vaccines are based on live attenuated viruses. An attractive idea is to genetically engineer these live attenuated vaccines so that they express protective antigens from other pathogens. Vaccinia virus, the smallpox vaccine, can be considered as the prototype for this sort of approach.
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La Revue du praticien, 1995
Live vaccines are composed of viral or bacterial strains which are deprived of their pathogenicity but can still replicate in the organism. These vaccines can provoke a non pathogenic infection in vaccinated subjects, both inducing an antibody and a cellular immune response.
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Live vaccines are composed of viral or bacterial strains which are deprived of their pathogenicity but can still replicate in the organism. These vaccines can provoke a non pathogenic infection in vaccinated subjects, both inducing an antibody and a cellular immune response.
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