Results 91 to 100 of about 267,671 (354)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Managing livelihood risks: Income diversification and the livelihood strategies of households in pastoral settlements in Isiolo County, Kenya [PDF]
Research in northern Kenya presents evidence that livestock herding remains the most important income activity for households in pastoral settlements, even though non-livestock income activities constitute a significant proportion of household income ...
Achiba, Gargule Andrew +1 more
core +1 more source
Cities, disasters and livelihoods [PDF]
This paper describes the impacts of recent disasters in urban areas and their contribution to poverty, and highlights how little attention urban development planning and disaster relief organizations give to disaster mitigation. It also describes CARE International’s Household Livelihood Security (HLS) model and how this allows an urban livelihoods ...
openaire +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Impact assessment in the Sustainable Livelihood Framework
The use of impact assessment can be characterised on a scale with ‘proving impact’ on one side and ‘improving practices’ on the other. Even though this is not an either/or scale, the two often do not combine automatically.
den Belder, Eefje +2 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Regional variation in livelihood strategies in Malawi [PDF]
Livelihood strategies are identified at the household level as a function of assets held, using survey data. Only endowments that are likely to be predetermined are included in the empirical analysis.
Magnus Hatlebakk
core
Comment: Healthcare and livelihoods [PDF]
In preparing a comment on these papers, it is the commonalities I seek though I am struck by some differences. The four research projects have been located in the Agincourt health and demographic surveillance site and are floated, as it were, upon the infrastructure of this site.
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Livelihood Cycle and Vulnerability of Rural Households to Climate Change and Hazards in Bangladesh
Rural riverine households in Bangladesh are confronted with many climate-driven hazards, including riverbank erosion, which results in loss of productive land and other natural resources of the riverine households, and thus threatens their livelihoods ...
Alam, G. M. Monirul
core +1 more source

