Results 91 to 100 of about 267,671 (354)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Managing livelihood risks: Income diversification and the livelihood strategies of households in pastoral settlements in Isiolo County, Kenya [PDF]

open access: yes, 2018
Research in northern Kenya presents evidence that livestock herding remains the most important income activity for households in pastoral settlements, even though non-livestock income activities constitute a significant proportion of household income ...
Achiba, Gargule Andrew   +1 more
core   +1 more source

Cities, disasters and livelihoods [PDF]

open access: yesEnvironment and Urbanization, 2000
This paper describes the impacts of recent disasters in urban areas and their contribution to poverty, and highlights how little attention urban development planning and disaster relief organizations give to disaster mitigation. It also describes CARE International’s Household Livelihood Security (HLS) model and how this allows an urban livelihoods ...
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Impact assessment in the Sustainable Livelihood Framework

open access: yes, 2012
The use of impact assessment can be characterised on a scale with ‘proving impact’ on one side and ‘improving practices’ on the other. Even though this is not an either/or scale, the two often do not combine automatically.
den Belder, Eefje   +2 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Regional variation in livelihood strategies in Malawi [PDF]

open access: yes
Livelihood strategies are identified at the household level as a function of assets held, using survey data. Only endowments that are likely to be predetermined are included in the empirical analysis.
Magnus Hatlebakk
core  

Comment: Healthcare and livelihoods [PDF]

open access: yesScandinavian Journal of Public Health, 2007
In preparing a comment on these papers, it is the commonalities I seek though I am struck by some differences. The four research projects have been located in the Agincourt health and demographic surveillance site and are floated, as it were, upon the infrastructure of this site.
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Livelihood Cycle and Vulnerability of Rural Households to Climate Change and Hazards in Bangladesh

open access: yes, 2017
Rural riverine households in Bangladesh are confronted with many climate-driven hazards, including riverbank erosion, which results in loss of productive land and other natural resources of the riverine households, and thus threatens their livelihoods ...
Alam, G. M. Monirul
core   +1 more source

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