Results 101 to 110 of about 267,671 (354)
Protecting rare, endemic, and endangered species requires careful habitat evaluation to set strategic plans for mitigating biodiversity loss and prioritizing conservation goals.
Kazi Al Muqtadir Abir +4 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Cities in Sub-Saharan Africa are undergoing massive socio-spatial transformations. Many old inner-city neighbourhoods are being demolished to give way to modern commercial and residential developments, and generally, to a more modern living environment ...
Alice Nikuze +3 more
semanticscholar +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Livelihood Risk from HIV in Semi-Arid Tropics of Rural Andhra Pradesh [PDF]
This paper discusses the livelihood dynamics in the fragile landscape of the semi arid tropics (SAT) of Andhra Pradesh. SAT is home to the poorest of the poor who live in conditions of persistent drought, subsistence agriculture and poor access to ...
Gandhi, B. Valentine Joseph +2 more
core +2 more sources
This study examined the sensory attributes and quality control properties of pasteurized coconut water. The study utilizes a quantitative research design.
Ikearl Jane B Pahilangco +3 more
doaj +1 more source
In our rapidly urbanizing world, the problem of rurality versus urbanization is becoming a source of concern. Rural tourism development may become a new important stimulus for promoting a sustainable transformation of the farmers’ livelihood.
Huiqin Li +3 more
semanticscholar +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

