Results 181 to 190 of about 267,671 (354)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Fisheries rehabilitation in post-tsunami Aceh: Status and needs from participatory appraisals [PDF]

open access: yes
The widespread and long-term nature of the tsunami damage in Aceh province, Indonesia has threatened the continued use of coastal and fisheries resources. This article describes the application of the Rapid Appraisal of Fisheries Management System (RAFMS)
Andrew, N.L.   +6 more
core  

Fluid Institutions of Access: Sea Space as a Livelihood Resource in Coastal Indonesia

open access: yes
Indonesia is the world's largest producer of carrageenan seaweed, the cultivation of which is dominated by household operators and is transforming livelihoods in many coastal communities.
Walyandra, Z   +6 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Extent of Livelihood Assets Influence on Livelihood Changes

open access: yesInternational Journal of Current Microbiology and Applied Sciences, 2020
K. Mahandrakumar   +2 more
openaire   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

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