Results 1 to 10 of about 3,269,800 (189)

Liver [PDF]

Modern Pathology, 2016
The median waiting time for patients with MELD ≥ 35 decreased from 18 days in 2012 to 9 days in 2014, after implementation of the Share 35 policy in June 2013. Similarly, mortality among candidates listed with MELD ≥ 35 decreased from 366 per 100 waitlist years in 2012 to 315 in 2014.
W R, Kim, J R, Lake, J M, Smith, M A, Skeans, D P, Schladt, E B, Edwards, A M, Harper, J L, Wainright, J J, Snyder, A K, Israni, B L, Kasiske   +10 more
  +9 more sources

Liver transplantation [PDF]

Current Opinion in Gastroenterology, 1998
Continued discussion over organ allocation and distribution remained a focal point in the field of liver transplantation in the year 2000. Despite the ongoing debate, no significant changes were implemented in the current allocation system. By far, the most widely discussed topic in liver transplantation this year was live donor adult-to-adult liver ...
Brown, KA, Moonka, DK
openaire   +6 more sources

Factors Prognostic of Survival in Liver Transplant Recipients with Hepatitis B Virus Related Acute-on-Chronic Liver Failure

Canadian Journal of Gastroenterology and Hepatology, 2022
Objectives. Factors prognostic of survival in liver transplant (LT) recipients with hepatitis B virus related acute-on-chronic liver failure (HBV-ACLF) remain unclear.
Zhengjun Zhou, Junfang Yi, Qiang Li, Wei Hu, Guangshun Chen, Zhongzhou Si, Jiequn Li   +6 more
doaj   +1 more source

NCSTN promotes hepatocellular carcinoma cell growth and metastasis via β-catenin activation in a Notch1/AKT dependent manner

Journal of Experimental & Clinical Cancer Research, 2020
Background Hepatocellular carcinoma is the third top cause of cancer-related mortalities worldwide. The prognosis of HCC patients remains poor due to rapid progression and high incidence of tumor recurrence.
Hui Li, Tian Lan, Lin Xu, Hailing Liu, Jinju Wang, Jiaxin Li, Xiangzheng Chen, Jiwei Huang, Xuefeng Li, Kefei Yuan, Yong Zeng, Hong Wu   +11 more
doaj   +1 more source

Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis

Cell Death and Disease, 2023
Multidrug resistance is a major challenge in treating advanced hepatocellular carcinoma (HCC). Although recent studies have reported that the multidrug resistance phenotype is associated with abnormal DNA methylation in cancer cells, the epigenetic ...
Xiao-Jun Guo, Xiao-Yong Huang, Xuan Yang, Jia-Cheng Lu, Chuan-Yuan Wei, Chao Gao, Yan-Zi Pei, Yi Chen, Qi-Man Sun, Jia-Bin Cai, Jian Zhou, Jia Fan, Ai-Wu Ke, Yujiang G. Shi, Ying-Hao Shen, Peng-Fei Zhang, Guo-Ming Shi, Guo-Huan Yang   +17 more
doaj   +1 more source

The role of RIPK1 mediated cell death in acute on chronic liver failure

Cell Death and Disease, 2021
Acute-on-chronic liver failure (ACLF) is characterized predominantly by non-apoptotic forms of hepatocyte cell death. Necroptosis is a form of programmed lytic cell death in which receptor interacting protein kinase (RIPK) 1, RIPK3 and phosphorylated ...
Takayuki Kondo, Stewart Macdonald, Cornelius Engelmann, Abeba Habtesion, Jane Macnaughtan, Gautam Mehta, Rajeshwar P. Mookerjee, Nathan Davies, Marco Pavesi, Richard Moreau, Paolo Angeli, Vicente Arroyo, Fausto Andreola, Rajiv Jalan   +13 more
doaj   +1 more source

Liver Anatomy: Microcirculation of the Liver [PDF]

Seminars in Interventional Radiology, 2008
Comprehension of the structural and functional characteristics of the hepatic microcirculation can help improve the design, planning, and practice of imaging-guided treatment for hepatic tumors and for portal vein embolization (PVE). The hepatic microcirculation derives dual blood supply from the portal vein and the hepatic artery.
Zuxing Kan, David C. Madoff
openaire   +2 more sources

Integrative analyses identify CD73 as a prognostic biomarker and immunotherapeutic target in intrahepatic cholangiocarcinoma

World Journal of Surgical Oncology, 2023
Background CD73 promotes progression in several malignancies and is considered as a novel immune checkpoint. However, the function of CD73 in intrahepatic cholangiocarcinoma (ICC) remains uncertain.
Bao-Ye Sun, Zhang-Fu Yang, Zhu-Tao Wang, Gao Liu, Cheng Zhou, Jian Zhou, Jia Fan, Wei Gan, Yong Yi, Shuang-Jian Qiu   +9 more
doaj   +1 more source

Peritumoral plasmacytoid dendritic cells predict a poor prognosis for intrahepatic cholangiocarcinoma after curative resection

Cancer Cell International, 2020
Background Plasmacytoid dendritic cells (pDCs) are present in various primary and metastatic human neoplasms; however, their clinical significance in intrahepatic cholangiocarcinoma is not clear.
Zhi-Qiang Hu, Zheng-Jun Zhou, Chu-Bin Luo, Hao-Yang Xin, Jia Li, Song-Yang Yu, Shao-Lai Zhou   +6 more
doaj   +1 more source

SQSTM1/p62 in intrahepatic cholangiocarcinoma promotes tumor progression via epithelial–mesenchymal transition and mitochondrial function maintenance

Cancer Medicine, 2023
Background SQSTM1/p62 is a selective autophagy receptor that regulates multiple signaling pathways participating in the initiation and progression of tumors.
Jiafeng Chen, Zheng Gao, Xiaogang Li, Yinghong Shi, Zheng Tang, Weiren Liu, Xin Zhang, Ao Huang, Xuanming Luo, Qiang Gao, Guangyu Ding, Kang Song, Jian Zhou, Jia Fan, Xiutao Fu, Zhenbin Ding   +15 more
doaj   +1 more source