Results 41 to 50 of about 3,097,477 (208)

Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection [PDF]

open access: yes, 2008
Autoimmune liver diseases, such as autoimmune hepatitis (AIH) and primary biliary cirrhosis, often have severe consequences for the patient. Because of a lack of appropriate animal models, not much is known about their potential viral etiology. Infection
Hintereder, Gudrun   +23 more
core   +1 more source

The Efficacy and Safety of Hepatic Arterial Infusion Chemotherapy Based on FOLFIRI for Advanced Intrahepatic Cholangiocarcinoma as Second-Line and Successive Treatment: A Real-World Study

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2022
Objective. Intrahepatic cholangiocarcinoma (iCCA) is a primary liver malignancy with a poor prognosis and limited treatment. Cisplatin with gemcitabine is used as the standard first-line chemotherapy regimen; however, there is still no robust evidence ...
Peixin Huang   +6 more
doaj   +1 more source

Integrative analyses identify CD73 as a prognostic biomarker and immunotherapeutic target in intrahepatic cholangiocarcinoma

open access: yesWorld Journal of Surgical Oncology, 2023
Background CD73 promotes progression in several malignancies and is considered as a novel immune checkpoint. However, the function of CD73 in intrahepatic cholangiocarcinoma (ICC) remains uncertain.
Bao-Ye Sun   +9 more
doaj   +1 more source

Dose adaptation of drugs in patients with liver disease [PDF]

open access: yes, 2009
A detailed introduction into the topic was obtained by developing a German-language online course named “Dose adjustment in Patients with Liver Disease” for the “Swiss Virtual Campus” in collaboration with PNN AG, a spin-off company of the ETH Zurich.
Schlatter-Häner, Chantal
core   +1 more source

Management of Wilson disease across Europe: an international physician-oriented survey by the ERN-RARE Liver group

open access: yesOrphanet Journal of Rare Diseases
Background Wilson disease (WD) is a rare disorder resulting in copper overload. Diagnosis and treatment are complex and highly specialized. We aimed to investigate the management of WD across Europe in line with the mission and framework of the European ...
Frederik Teicher Kirk   +14 more
doaj   +1 more source

Tumor-associated macrophages modulate resistance to oxaliplatin via inducing autophagy in hepatocellular carcinoma

open access: yesCancer Cell International, 2019
Background Oxaliplatin-based chemotherapy is widely used to treat hepatocellular carcinoma (HCC). Recent studies suggested that therapeutic resistance of tumors was affected by tumor microenvironment (TME).
Xiu-Tao Fu   +9 more
doaj   +1 more source

Liver resections for liver transplantations

open access: yesWorld Journal of Gastrointestinal Surgery, 2010
Split-Liver and living-related donor liver transplantation are the newest and both technically and ethically most challenging developments in liver transplantation and have contributed to a reduction in donor shortage. We report the technical aspects of surgical procedures performed to achieve a partial graft from a cadaveric and a live donor.
GRUTTADAURIA, Salvatore Giovanni   +7 more
openaire   +3 more sources

Toward a future role for liver biopsy in HCC: literature evidence and survey-based perspectives from Korean experts [PDF]

open access: yesJournal of Liver Cancer
The role of liver biopsy in hepatocellular carcinoma (HCC) is being re-evaluated in the era of precision oncology and biomarker-driven systemic therapy.
Hae Lim Lee   +37 more
doaj   +1 more source

Living Donor Liver Transplantation in a Korean Child with Glycogen Storage Disease Type IV and a GBE1 Mutation. [PDF]

open access: yes, 2009
Glycogen storage disease type IV (GSD-IV) is an autosomal recessive disease caused by a deficient glycogen branching enzyme (GBE), encoded by the GBE1 gene, resulting in the accumulation of abnormal glycogen deposits in the liver and other tissues.
박영년, 정기섭, 고홍
core   +1 more source

An Unforeseen Diagnosis After Liver Transplantation for Acute Liver Failure: Extranodal NK/T-Cell Lymphoma

open access: yesCase Reports in Hepatology
Acute liver failure (ALF) is a medical emergency characterized by hepatic encephalopathy in patients with recent-onset jaundice and coagulopathy. We present a case of a patient who developed ALF secondary to NK/T-cell lymphoma, with the diagnosis ...
Giulia L. Soares   +12 more
doaj   +1 more source

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