Results 11 to 20 of about 332,718 (290)

Coating Membranes for a Sorbent-Based Artificial Liver: Adsorption Characteristics [PDF]

open access: yes, 1982
Techniques are described for the coating of sorbents to be used in an artificial liver support system based on mixed sorbent bed hemoperfusion. Activated charcoal has been coated with cellulose acetate (CA) by solvent evaporation.
Bantjes, Adriaan   +2 more
core   +6 more sources

M2-like macrophages exert hepatoprotection in acute-on-chronic liver failure through inhibiting necroptosis-S100A9-necroinflammation axis

open access: yesCell Death and Disease, 2021
Necroptosis has emerged as a novel and crucial player in acute and chronic liver diseases. Necroptotic cells lead to the release of DAMPs including S100A9, followed by the development of necroinflammation.
Li Bai   +5 more
doaj   +1 more source

Combined Effects of UGT1A1 and SLCO1B1 Variants on Chinese Adult Mild Unconjugated Hyperbilirubinemia

open access: yesFrontiers in Genetics, 2019
The potential for genetic variation to cause adult unconjugated hyperbilirubinemia is increasingly being recognized. However, the cumulative effects of genetic variants have not been fully illuminated.
Jie Bai   +12 more
doaj   +1 more source

Dynamic changes of phenotype and function of natural killer cells in peripheral blood before and after thermal ablation of hepatitis B associated hepatocellular carcinoma and their correlation with tumor recurrence

open access: yesBMC Cancer, 2023
Background Thermal therapy induces an immune response in patients with hepatocellular carcinoma (HCC), but the dynamic characteristics of the natural killer (NK) cell immune response post-thermal ablation remain unclear.
Hai-Yan Wang   +6 more
doaj   +1 more source

Artificial rearing influences the morphology, permeability and redox state of the gastrointestinal tract of low and normal birth weight piglets [PDF]

open access: yes, 2017
Background: In this study the physiological implications of artificial rearing were investigated. Low (LBW) and normal birth weight (NBW) piglets were compared as they might react differently to stressors caused by artificial rearing.
Casteleyn, Christophe   +9 more
core   +1 more source

Drug-Induced Nephrotoxicity Assessment in 3D Cellular Models

open access: yesMicromachines, 2021
The kidneys are often involved in adverse effects and toxicity caused by exposure to foreign compounds, chemicals, and drugs. Early predictions of these influences are essential to facilitate new, safe drugs to enter the market.
Pengfei Yu   +6 more
doaj   +1 more source

Two adolescent cases of early use of Molecular Adsorbent Recirculating System for drug-induced fulminant hepatic failure [PDF]

open access: yesPediatric Emergency Medicine Journal
Fulminant hepatic failure (FHF) is a rare but fatal disease with a 40%-80% mortality, often requiring liver transplantation, which is hard to perform in children.
Seo Yeon Kim, Beom Joon Kim
doaj   +1 more source

Application of 3D Hepatic Plate-Like Liver Model for Statin-Induced Hepatotoxicity Evaluation

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Background: Drug-induced liver injury is one of the main reasons of withdrawals of drugs in postmarketing stages. However, an experimental model(s) which can accurately recapitulates liver functions and reflects the level of drug hepatotoxicity is lack ...
Jiecheng Xu   +13 more
doaj   +1 more source

A dynamic prediction model for prognosis of acute-on-chronic liver failure based on the trend of clinical indicators

open access: yesScientific Reports, 2021
Acute-on-chronic liver failure (ACLF) is a dynamic syndrome, and sequential assessments can reflect its prognosis more accurately. Our aim was to build and validate a new scoring system to predict short-term prognosis using baseline and dynamic data in ...
Zhenjun Yu   +11 more
doaj   +1 more source

An Object-Oriented Approach to Knowledge Representation in a Biomedical Domain [PDF]

open access: yes, 1994
An object-oriented approach has been applied to the different stages involved in developing a knowledge base about insulin metabolism. At an early stage the separation of terminological and assertional knowledge was made. The terminological component was
Ensing, M.   +4 more
core   +2 more sources

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