Results 21 to 30 of about 332,718 (290)

The landscape of viral associations in human cancers [PDF]

open access: yes, 2020
Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for which whole-genome and—for a subset—whole-transcriptome sequencing data from 2,658 cancers across 38 tumor types was aggregated, we systematically investigated potential ...
Alawi, Malik   +14 more
core   +3 more sources

Fibrosis progression in interferon treatment-naive Chinese plasma donors with chronic hepatitis C for 20 years: a cohort study

open access: yesInternational Journal of Infectious Diseases, 2014
Objectives: To evaluate the progression of fibrosis and factors influencing this in interferon (IFN) treatment-naive Chinese plasma donors infected with hepatitis C virus (HCV) for approximately 20 years.
Jun-Feng Li   +10 more
doaj   +1 more source

Therapeutic Potential of CUDC-907 (Fimepinostat) for Hepatocarcinoma Treatment Revealed by Tumor Spheroids-Based Drug Screening

open access: yesFrontiers in Pharmacology, 2021
Background: Cancer is the second leading cause of death globally. However, most of the new anti-cancer agents screened by traditional drug screening methods fail in the clinic because of lack of efficacy.
Wei Liao   +16 more
doaj   +1 more source

Safety and Efficacy of Radiofrequency Ablation with Artificial Ascites for Hepatocellular Carcinoma [PDF]

open access: yes, 2012
The artificial ascites technique is often used during radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) treatment because it prevents visceral damage and improves visualization by minimizing interference of the lungs and mesentery.
Higashi, Toshihiro   +7 more
core   +1 more source

Inhibition of 5-Lipoxygenase Pathway Attenuates Acute Liver Failure by Inhibiting Macrophage Activation

open access: yesJournal of Immunology Research, 2014
This study aimed to investigate the role of 5-lipoxygenase (5-LO) in acute liver failure (ALF) and changes in macrophage activation by blocking it. ALF was induced in rats by administration of D-galactosamine (D-GalN)/lipopolysaccharide (LPS).
Lu Li   +11 more
doaj   +1 more source

Issues of intensive care and liver transplantation tactics in fulminant liver failure

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
Fulminant liver failure is usually characterized as severe acute liver injury with encephalopathy and synthetic dysfunction (international normalized ratio [INR] ≥1.5) in a patient without cirrhosis or previous liver disease.
L. U. Agumava   +10 more
doaj   +1 more source

Lineage tracing: technology tool for exploring the development, regeneration, and disease of the digestive system

open access: yesStem Cell Research & Therapy, 2020
Lineage tracing is the most widely used technique to track the migration, proliferation, and differentiation of specific cells in vivo. The currently available gene-targeting technologies have been developing for decades to study organogenesis, tissue ...
Yue Zhang   +4 more
doaj   +1 more source

Association of Serum Bilirubin With Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Endocrinology, 2022
ObjectiveMetabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD) are the leading chronic diseases worldwide. There are still many controversies about the association between serum bilirubin and MetS or NAFLD.
Chen Liang   +14 more
doaj   +1 more source

Flow competition between hepatic arterial and portal venous flow during hypothermic machine perfusion preservation of porcine livers [PDF]

open access: yes, 2012
Hypothermic machine perfusion (HMP) is regarded as a better preservation method for donor livers than cold storage. During HMP, livers are perfused through the inlet blood vessels, namely the hepatic artery (HA) and the portal vein (PO.
Debbaut, Charlotte   +6 more
core   +2 more sources

Correlation Between Circulating Tumor Cell DNA Genomic Alterations and Mesenchymal CTCs or CTC-Associated White Blood Cell Clusters in Hepatocellular Carcinoma

open access: yesFrontiers in Oncology, 2021
PurposeLiquid biopsy is attracting attention as a method of real-time monitoring of patients with tumors. It can be used to understand the temporal and spatial heterogeneity of tumors and has good clinical application prospects. We explored a new type of
Chunming Wang   +7 more
doaj   +1 more source

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