Results 41 to 50 of about 332,718 (290)

Age-specific reference values for low psoas muscle index at the L3 vertebra level in healthy populations: A multicenter study

Frontiers in Nutrition, 2022
Background and aimsThe progressive and generalized loss of skeletal muscle mass, strength and physical function is defined as sarcopenia. Sarcopenia is closely related to the prognosis of patients. Accurate diagnosis and adequate management of sarcopenia
Ming Kong, Ning Lin, Lili Wang, Nan Geng, Manman Xu, Shanshan Li, Wenyan Song, Ying Zhou, Yuetong Piao, Zuoqing Han, Rong Guo, Chao Yang, Nan Luo, Zhong Wang, Quanxiao Xu, Daimeng Shi, Wanchun Qiu, Junfeng Li, Eddie C. Cheung, Eddie C. Cheung, Lei Ma, Yu Chen, Zhongping Duan   +22 more
doaj   +1 more source

ANN for Diagnosing Hepatitis Virus [PDF]

, 2017
: This paper presents an artificial neural network based approach for the diagnosis of hepatitis virus. A number of factors that may possibly influence the performance of patients were outlined.
AbuSharekh, Khaled, Bashhar, Bastami, Metwally, Fathi   +2 more
core  

Simulation of hyperelastic materials in real-time using Deep Learning [PDF]

, 2019
The finite element method (FEM) is among the most commonly used numerical methods for solving engineering problems. Due to its computational cost, various ideas have been introduced to reduce computation times, such as domain decomposition, parallel ...
Cotin, Stéphane, Mendizabal, Andrea, Márquez-Neila, Pablo   +2 more
core   +5 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Employing hypoxia characterization to predict tumour immune microenvironment, treatment sensitivity and prognosis in hepatocellular carcinoma

Computational and Structural Biotechnology Journal, 2021
The hypoxic microenvironment was recognized as a major driving force of the malignant phenotype in hepatocellular carcinoma (HCC), which contributes to tumour immune microenvironment (TIM) remodeling and tumor progression.
Fanhong Zeng, Yue Zhang, Xu Han, Min Zeng, Yi Gao, Jun Weng   +5 more
doaj   +1 more source

Surgical technique of orthotopic liver transplantation [PDF]

, 1988
Athough significant strides have been made in the surgical technique of orthotopic liver transplantation, numerous problems and nuisances are still encountered. Further surgical refinements will certainly evolve.
Bowman, J, Kahn, D, Makowka, L, Mieles, L, Sher, L, Starzl, TE, Stieber, AC, Wallis Marsh, J   +7 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Advancements in stem cell-derived hepatocyte-like cell models for hepatotoxicity testing

Stem Cell Research & Therapy, 2021
Drug-induced liver injury (DILI) is one of the leading causes of clinical trial failures and high drug attrition rates. Currently, the commonly used hepatocyte models include primary human hepatocytes (PHHs), animal models, and hepatic cell lines ...
Meixian Jin, Xiao Yi, Wei Liao, Qi Chen, Wanren Yang, Yang Li, Shao Li, Yi Gao, Qing Peng, Shuqin Zhou   +9 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Risk factors for the development of cirrhosis within 1-year in non-cirrhotic patients with HBV- related acute-on-chronic liver failure

Frontiers in Medicine
Aims and BackgroundThis study aimed to provide a preliminary clarification of the predictive factors for the development of cirrhosis within 1-year cirrhosis in non-cirrhotic HBV-associated acute-on-chronic liver failure (HBV-ACLF) patients and develop a
Wenling Wang, Wenling Wang, Xiaolin Wang, Xiaolin Wang, Yu Wu, Yu Wu, Huaibin Zou, Huaibin Zou, Manman Xu, Manman Xu, Yu Chen, Yu Chen   +11 more
doaj   +1 more source