Results 31 to 40 of about 3,269,800 (189)

Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study [PDF]

, 2015
Background & AimsIn acute liver failure, severity of liver injury and clinical progression of disease are in part consequent upon activation of the innate immune system.
Aggarwal, Antoine, B. Kevin Park, Banares, Banwari Agarwal, Carolina Jimenez Palacios, Christopher E. Goldring, Daniel J. Antoine, D’Souza, Fausto Andreola, Fisher, Garcia-Martinez, Giacomo Stanzani, Hatim Alibhai, Honore, Imaeda, Jaeschke, Jalan, Jalan, Karla C.L. Lee, Kribben, Lee, Lee, Liu, Lu, Luisa A. Baker, Maher, Martin-Murphy, Millis, Mookerjee, Morgera, Morgera, Morgera, Morgera, Morgera, Nathan A. Davies, Nystrom, Oettl, Oettl, Pamela J. Leckie, Paola Giordano, Rademacher, Rajeshwar P. Mookerjee, Rajiv Jalan, Rifai, Rimmele, Rosalind E. Jenkins, Saliba, Scaffidi, Sen, Shah, Simon L. Priestnall, Simpson, Stadlbauer, Su, Su, Szabo, Vaquero, Venereau, Yang, Yu Mei Chang, Yumoto   +61 more
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The role of lipid and lipoprotein metabolism in non-alcoholic fatty liver disease [PDF]

, 2017
Due to the epidemic of obesity across the world, nonalcoholic fatty liver disease (NAFLD) has become one of the most prevalent chronic liver disorders in children and adolescents.
Anania, Caterina, Lavorato, Michela, Perla, Francesco Massimo, Prelati, Maurizia, Visicchio, Daniele   +4 more
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PCSK9 promotes tumor growth by inhibiting tumor cell apoptosis in hepatocellular carcinoma

Experimental Hematology & Oncology, 2021
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9), one of the key enzymes in the process of lipid transport, is involved in the disease progression of various types of tumors.
Shi-Zhe Zhang, Xiao-Dong Zhu, Long-Hai Feng, Xiao-Long Li, Xue-Feng Liu, Hui-Chuan Sun, Zhao-You Tang   +6 more
doaj   +1 more source

The impact of thrombocytopenia on prognosis of HBV-related small hepatocellular carcinoma: a propensity score matching analysis

World Journal of Surgical Oncology, 2021
Background Thrombocytopenia was reported both detrimental and advantageous to hepatocellular carcinoma (HCC). However, there is little evidence showing clearly the clinical value of preoperative thrombocytopenia on the surgical outcome of patients with ...
Wei Peng, Chuan Li, Xiaoyun Zhang, Tianfu Wen, Zheyu Chen   +4 more
doaj   +1 more source

CD4+CD25+CD127low regulatory T cells play predominant anti-tumor suppressive role in hepatitis B virus associated hepatocellular carcinoma

Frontiers in Immunology, 2015
Background:Hepatocellular carcinoma (HCC) is the second leading cause of cancer death worldwide and hepatitis B is one of the commonest causes. T regulatory cells (Tregs) are strong immunomodulators and are likely to play a major role in HCC development.
Shreya eSharma, Ritu eKhosla, Paul eDavid, Archana eRastogi, Ashish eVyas, Dileep eSingh, Ankit eBhardwaj, Amrish eSahney, Rakhi eMaiwall, Shiv Kumar Sarin, Nirupma eTrehanpati   +10 more
doaj   +1 more source

Post-Transcriptional Regulation of Hepatic DDAH1 with TNF Blockade Leads to Improved eNOS Function and Reduced Portal Pressure In Cirrhotic Rats

Scientific Reports, 2017
Portal hypertension (PH) is a major cause of morbidity and mortality in chronic liver disease. Infection and inflammation play a role in potentiating PH and pro-inflammatory cytokines, including TNF, are associated with severity of PH.
V. Balasubramanian, G. Mehta, H. Jones, V. Sharma, N. A. Davies, R. Jalan, R. P. Mookerjee   +6 more
doaj   +1 more source

Serial circulating tumor DNA to predict early recurrence in patients with hepatocellular carcinoma: a prospective study

Molecular Oncology, 2022
We studied the value of circulating tumor DNA (ctDNA) in predicting early postoperative tumor recurrence and monitoring tumor burden in patients with hepatocellular carcinoma (HCC).
Gui‐Qi Zhu, Wei‐Ren Liu, Zheng Tang, Wei‐Feng Qu, Yuan Fang, Xi‐Fei Jiang, Shu‐Shu Song, Han Wang, Chen‐Yang Tao, Pei‐Yun Zhou, Run Huang, Jun Gao, Hai‐Xiang Sun, Zhen‐Bin Ding, Yuan‐Fei Peng, Zhi Dai, Jian Zhou, Jia Fan, Ying‐Hong Shi   +18 more
doaj   +1 more source

Tumor-associated macrophages modulate resistance to oxaliplatin via inducing autophagy in hepatocellular carcinoma

Cancer Cell International, 2019
Background Oxaliplatin-based chemotherapy is widely used to treat hepatocellular carcinoma (HCC). Recent studies suggested that therapeutic resistance of tumors was affected by tumor microenvironment (TME).
Xiu-Tao Fu, Kang Song, Jian Zhou, Ying-Hong Shi, Wei-Ren Liu, Guo-Ming Shi, Qiang Gao, Xiao-Ying Wang, Zhen-Bin Ding, Jia Fan   +9 more
doaj   +1 more source

Changes of fatty acid metabolism and oxidative phosphorylation of rat liver mitochondria during 3'-Me-DAB feeding [PDF]

, 1964
Respiration, activity of oleate oxidation and composition of the total fatty acids of rat liver were investigated in 3'-Me-DAB feeding. 1. Oxidative phosphorylation of rat liver mitochondria decreased temporarily at relatively earlier stages (about 2 to ...
Inaba, Kozo
core   +1 more source

Acute-on-chronic Liver Failure: MELD Score 30-day Mortality Predictability and Etiology in a Pakistani Population [PDF]

, 2020
Background: Cirrhosis is a pathological condition that ultimately leads to liver failure. Acute on chronic liver failure (ACLF) has a high short term mortality rate. Viral hepatitis is the most common cause of liver failure in our local population.
Gilani, N. A. (Naeem), Khalid, T. (Talha), Sarfraz, A. (Azza), Sarfraz, M. (Muzna), Sattar, S. (Saim), Siddiq, J. (Javaria)   +5 more
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