Results 31 to 40 of about 4,157,738 (198)

Post-Transcriptional Regulation of Hepatic DDAH1 with TNF Blockade Leads to Improved eNOS Function and Reduced Portal Pressure In Cirrhotic Rats

Scientific Reports, 2017
Portal hypertension (PH) is a major cause of morbidity and mortality in chronic liver disease. Infection and inflammation play a role in potentiating PH and pro-inflammatory cytokines, including TNF, are associated with severity of PH.
V. Balasubramanian, G. Mehta, H. Jones, V. Sharma, N. A. Davies, R. Jalan, R. P. Mookerjee   +6 more
doaj   +1 more source

Serial circulating tumor DNA to predict early recurrence in patients with hepatocellular carcinoma: a prospective study

Molecular Oncology, 2022
We studied the value of circulating tumor DNA (ctDNA) in predicting early postoperative tumor recurrence and monitoring tumor burden in patients with hepatocellular carcinoma (HCC).
Gui‐Qi Zhu, Wei‐Ren Liu, Zheng Tang, Wei‐Feng Qu, Yuan Fang, Xi‐Fei Jiang, Shu‐Shu Song, Han Wang, Chen‐Yang Tao, Pei‐Yun Zhou, Run Huang, Jun Gao, Hai‐Xiang Sun, Zhen‐Bin Ding, Yuan‐Fei Peng, Zhi Dai, Jian Zhou, Jia Fan, Ying‐Hong Shi   +18 more
doaj   +1 more source

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease.

Journal of Clinical Investigation, 2005
Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of excess liver triacylglycerol (TAG), inflammation, and liver damage.
Kerry L Donnelly, Coleman I. Smith, S. Schwarzenberg, J. Jessurun, M. Boldt, E. Parks   +5 more
semanticscholar   +1 more source

Hypothermic Machine Perfusion in Liver Transplantation - A Randomized Trial.

New England Journal of Medicine, 2021
BACKGROUND Transplantation of livers obtained from donors after circulatory death is associated with an increased risk of nonanastomotic biliary strictures.
R. van Rijn, Ivo J. Schurink, Y. de Vries, A. P. van den Berg, M. Cortés Cerisuelo, S. Darwish Murad, J. Erdmann, N. Gilbo, R. D. de Haas, N. Heaton, B. van Hoek, V. Huurman, I. Jochmans, O. B. van Leeuwen, V. D. de Meijer, D. Monbaliu, W. Polak, J. Slangen, R. Troisi, A. Vanlander, J. de Jonge, R. Porte   +21 more
semanticscholar   +1 more source

Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease.

Gastroenterology, 2015
BACKGROUND & AIMS Histologic analysis of liver biopsy specimens allows for grading and staging of nonalcoholic fatty liver disease (NAFLD). We performed a longitudinal study to investigate the long-term prognostic relevance of histologic features for ...
P. Angulo, D. Kleiner, S. Dam-Larsen, L. Adams, E. Bjornsson, P. Charatcharoenwitthaya, P. Mills, Jill C. Keach, H. Lafferty, Alisha Stahler, Svanhildur Haflidadottir, F. Bendtsen   +11 more
semanticscholar   +1 more source

Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway

Cell Death Discovery, 2022
Hepatocellular carcinoma (HCC) is one of the most serious malignant cancers and has a high fatality rate. However, clinical strategies for the effective treatment of HCC remain lacking.
Bo Xu, Yonggang Wei, Fei Liu, Lian Li, Siqi Zhou, Yufu Peng, Bo Li   +6 more
doaj   +1 more source

Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease

Hepatology, 2017
Nonalcoholic fatty liver disease (NAFLD) and resulting nonalcoholic steatohepatitis (NASH) are highly prevalent in the United States, where they are a growing cause of cirrhosis and hepatocellular carcinoma (HCC) and increasingly an indicator for liver ...
C. Estes, H. Razavi, R. Loomba, Z. Younossi, A. Sanyal   +4 more
semanticscholar   +1 more source

Macrophage Polarization and Its Role in Liver Disease

Frontiers in Immunology, 2021
Macrophages are important immune cells in innate immunity, and have remarkable heterogeneity and polarization. Under pathological conditions, in addition to the resident macrophages, other macrophages are also recruited to the diseased tissues, and ...
Cheng Wang, Cheng Ma, Lihong Gong, Yuqin Guo, K. Fu, Yafang Zhang, Honglin Zhou, Yunxia Li   +7 more
semanticscholar   +1 more source

Assessment of hepatic steatosis of potential living donor before liver transplantation using liver/spleen CT attenuation ratio compared to liver biopsy

The Egyptian Journal of Radiology and Nuclear Medicine, 2023
Background Hepatic steatosis has become a major worldwide health problem, so assessment of hepatic steatosis in potential living donors is crucial prior to liver transplantation.
Hesham Mohamed Atef, Enas Mohamed Korayem, Naglaa Allam Ahmed, Mohamed Mohamed Houseni, Ahmed Mohamed El-Refaie, Manal Ibrahim Gomaa   +5 more
doaj   +1 more source

A High-Accuracy Model Based on Plasma miRNAs Diagnoses Intrahepatic Cholangiocarcinoma: A Single Center with 1001 Samples

Diagnostics, 2021
Objectives: Intrahepatic cholangiocarcinoma (iCCA) is a highly malignant cancer. More than 70% of patients are diagnosed at an advanced stage. The aim of this study was to evaluate the diagnostic value of plasma miR-21, miR-122, and CA19-9, hoping to ...
Jie Hu, Yi-Ning Wang, Dan-Jun Song, Jin-Peng Tan, Ya Cao, Jia Fan, Zheng Wang, Jian Zhou   +7 more
doaj   +1 more source