Results 171 to 180 of about 119,037 (316)
N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen +6 more
wiley +1 more source
A Rare Nonsense Mutation in the ABCB4 Gene Associated with Progressive Familial Intrahepatic Cholestasis Type 3: A Case Report. [PDF]
Cai B, Lv D, Luo X, Zhou L.
europepmc +1 more source
Gut microbiome‐derived metabolites show promise in cancer research and therapy
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang +4 more
wiley +1 more source
A liver function test pathway significantly increases the early detection of chronic liver disease and cirrhosis. [PDF]
Gao J +5 more
europepmc +1 more source
A Comparative Study of Ultrasonography and CT Venography in the Diagnosis of Budd‐Chiari Syndrome
Budd‐Chiari syndrome (BCS) is characterized by hepatic venous outflow obstruction from the hepatic veins to the junction of the inferior vena cava (IVC) and right atrium. Ultrasound (US) and CT venography (CTV) are used as imaging techniques for the diagnosis of BCS, and We compared the diagnostic efficacy of the two modalities. The results showed that
Tiling Jiang +6 more
wiley +1 more source
Hepatitis B virus, alcohol, and liver cancer. [PDF]
Pathania AS, Osna NA.
europepmc +1 more source
Abstract Background Routine in‐hospital screening of social risk factors linked with poor health outcomes is not done in Singapore, where an aging population pays for 25% healthcare costs out‐of‐pocket despite universal coverage. Objective We developed and implemented a social risk screening tool for hospitalised patients and reported the association ...
Orlanda Q. M. Goh +10 more
wiley +1 more source

