Results 131 to 140 of about 11,978,501 (365)

Non-alcoholic fatty liver disease in pregnancy is associated with adverse maternal and perinatal outcomes

, 2020
Monika Sarkar, Joshua D. Grab, Jennifer L. Dodge, Erica P. Gunderson, Jessica B. Rubin, Roxanna A. Irani, Marcelle I. Cedars, Norah A. Terrault   +7 more
openalex   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Hepatitis B virus-infected hepatocytes promote the secretion of collagen VI to the extracellular matrix

Scientific Reports
Chronic hepatitis B virus (HBV) infection is a global health problem as it is the major cause of liver fibrosis and its complications cirrhosis and hepatocellular carcinoma.
Alessia Virzì, Zakaria Boulahtouf, Julien Moehlin, Lea Girard, Laura Meiss-Heydmann, Charlotte Bach, Emma Gerges, Sarah C. Durand, Marine A. Oudot, Armando A. Roca Suarez, Oliver Popp, Evelyn Ramberger, Philipp Mertins, Emanuele Felli, Patrick Pessaux, Catherine Schuster, Eloi R. Verrier, Thomas F. Baumert, Joachim Lupberger   +18 more
doaj   +1 more source

Cell Models and Omics Techniques for the Study of Nonalcoholic Fatty Liver Disease: Focusing on Stem Cell-Derived Cell Models [PDF]

, 2021
María Pelechá, Estela Villanueva-Bádenas, Enrique Timor-López, M. Teresa Donato, Laia Tolosa   +4 more
openalex   +1 more source

Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes

Hepatology, 2016
Z. Younossi, Aaron B Koenig, Dinan Abdelatif, Yousef Fazel, L. Henry, M. Wymer   +5 more
semanticscholar   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

IL-18 But Not IL-1 Signaling Is Pivotal for the Initiation of Liver Injury in Murine Non-Alcoholic Fatty Liver Disease [PDF]

, 2020
Simon Hohenester, Veronika Kanitz, Tobias S. Schiergens, Claudia Einer, J. Nagel, Ralf Wimmer, Florian P. Reiter, Alexander L. Gerbes, Enrico N. De Toni, Christian Bauer, Lesca M. Holdt, Doris Mayr, Christian Rust, Max Schnurr, Hans Zischka, Andreas Geier, Gerald Denk   +16 more
openalex   +1 more source

The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition [PDF]

, 2022
Dennis van der Meer, Tiril P. Gurholt, Ida E. Sønderby, Alexey Shadrin, Guy Hindley, Zillur Rahman, Ann‐Marie G. de Lange, Oleksandr Frei, Olof Dahlqvist Leinhard, Jennifer Linge, Rozalyn Simon, Dani Beck, Lars T. Westlye, Sigrun Halvorsen, Anders M. Dale, Tom H. Karlsen, Tobias Kaufmann, Ole A. Andreassen   +17 more
openalex   +1 more source

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

Hepatology, 2018
N. Chalasani, Z. Younossi, J. Lavine, M. Charlton, K. Cusi, M. Rinella, S. Harrison, E. Brunt, A. Sanyal   +8 more
semanticscholar   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source