Results 131 to 140 of about 12,541,927 (431)

Noninvasive Assessment of Liver Disease in Patients With Nonalcoholic Fatty Liver Disease.

Gastroenterology, 2019
Nonalcoholic fatty liver disease (NAFLD) is estimated to afflict approximately 1 billion individuals worldwide. In a subset of NAFLD patients, who have the progressive form of NAFLD termed nonalcoholic steatohepatitis (NASH), it can progress to advanced ...
L. Castéra, M. Friedrich-Rust, R. Loomba   +2 more
semanticscholar   +1 more source

Pre-existing liver disease is associated with poor outcome in patients with SARS CoV2 infection; The APCOLIS Study (APASL COVID-19 Liver Injury Spectrum Study)

Hepatology International, 2020
Background and aims COVID-19 is a dominant pulmonary disease, with multisystem involvement, depending upon comorbidities. Its profile in patients with pre-existing chronic liver disease (CLD) is largely unknown.
S. Sarin, A. Choudhury, G. Lau, M. Zheng, D. Ji, S. Abd-Elsalam, Jaeseok Hwang, X. Qi, I. Cua, J. Suh, O. Putcharoen, A. Kaewdech, T. Piratvisuth, S. Treeprasertsuk, S. Park, Salisa Wejnaruemarn, D. Payawal, O. Baatarkhuu, S. Ahn, C. Yeo, Uzziel Romar Alonzo, Tserendorj Chinbayar, I. Loho, O. Yokosuka, W. Jafri, S. Tan, Lau Ing Soo, T. Tanwandee, R. Gani, Lovkesh Anand, E. Esmail, M. Khalaf, Shahinul Alam, Chun-Yu Lin, W. Chuang, A. Soin, H. Garg, K. Kalista, Badamnachin Batsukh, Hery Djagat Purnomo, V. Dara, P. Rathi, M. Mahtab, A. Shukla, M. Sharma, M. Omata, Apasl Covid Task Force, Apasl Covid Liver Injury Spectrum Study   +47 more
semanticscholar   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Lafora Disease Masquerading as Hepatic Dysfunction [PDF]

, 2018
Lafora disease is fatal intractable progressive myoclonic epilepsy. It is frequently characterized by epileptic seizures, difficulty walking, muscle spasms, and dementia in late childhood or adolescence.
Abdullah, Hafez Mohammad A., Ali, Nouman Safdar, Ilyas, Ghulam, Inayat, Faisal, Khan, Zarak H., Lodhi, Hanan T., Ullah, Waqas   +6 more
core   +1 more source

Oxidative stress: new insights on the association of nonalcoholic fatty liver disease and atherosclerosis [PDF]

, 2015
Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH), which may progress ...
Albanese, Fabiana, Angelico, Francesco, Baratta, Francesco, DEL BEN, Maria, Pastori, Daniele, Perri, Ludovica, Polimeni, Licia, Violi, Francesco   +7 more
core   +1 more source

Angiogenesis in liver disease

Journal of Hepatology, 2009
Angiogenesis and disruption of liver vascular architecture have been linked to progression to cirrhosis and liver cancer (HCC) in chronic liver diseases, which contributes both to increased hepatic vascular resistance and portal hypertension and to decreased hepatocyte perfusion.
Fernández, Mercedes, Semela, David, Bruix, Jordi, Colle, Isabelle, Pinzani, Massimo, Bosch, Jaume   +5 more
openaire   +4 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Waist circumference in Liver Disease [PDF]

, 2016
Background Central fat accumulation is important in Non-alcoholic Fatty Liver Disease (NAFLD) etiology. It is unknown weather any commonly used waist circumference (WC) measurement protocol (mp), as whole and central fat accumulation marker, is ...
Cortez-Pinto, Helena, Melo, Xavier, Pimenta, Nuno, Santa-Clara, Helena, Sardinha, Luis, Silva Nunes, José António   +5 more
core   +1 more source