Results 31 to 40 of about 11,978,501 (365)

Integrated analysis of 1804 samples of six centers to construct and validate a robust immune-related prognostic signature associated with stromal cell abundance in tumor microenvironment for gastric cancer

World Journal of Surgical Oncology, 2022
Background Stromal cells in tumor microenvironment could promote immune escape through a variety of mechanisms, but there are lacking research in the field of gastric cancer (GC). Methods We identified differential expressed immune-related genes (DEIRGs)
Junyu Huo, Ge Guan, Jinzhen Cai, Liqun Wu   +3 more
doaj   +1 more source

Droxinostat, a Histone Deacetylase Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cell Lines via Activation of the Mitochondrial Pathway and Downregulation of FLIP

Translational Oncology, 2016
Background: The current chemotherapeutic outcomes for hepatocellular carcinoma (HCC) are not encouraging, and long-term survival of this patient group remains poor.
Jing Liu, Guangming Li, Xiang Wang, Liang Wang, Rui Zhao, Juanxia Wang, Yin Kong, Jie Ding, Juan Li, Lingyi Zhang   +9 more
doaj   +1 more source

Efficacy and safety of Anluohuaxian in the treatment of patients with severe Coronavirus disease 2019- a multicenter, open label, randomized controlled study: a structured summary of a study protocol for a randomised controlled trial

Trials, 2020
Objectives Patients with severe COVID-19 often suffer from significant pulmonary fibrosis. Although the pathogenesis of pulmonary fibrosis has not been fully explained, the signal pathways and cytokines involved are very similar to hepatic fibrosis. This
Chi Zhang, Jiawen Li, Zhao Wu, He Wang, Chengli Que, Hong Zhao, Guiqiang Wang   +6 more
doaj   +1 more source

Eight-gene metabolic signature related with tumor-associated macrophages predicting overall survival for hepatocellular carcinoma

BMC Cancer, 2021
Background In recent years, the relationship between tumor-associated macrophages (TAMs) and solid tumors has become a research hotspot. This study aims to explore the close relationship of TAMs with metabolic reprogramming genes in hepatocellular ...
Junyu Huo, Liqun Wu, Yunjin Zang, Hongjing Dong, Xiaoqiang Liu, Fu He, Xiao Zhang   +6 more
doaj   +1 more source

Global Perspectives on Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

Hepatology, 2019
Over the past 2 decades, nonalcoholic fatty liver disease (NAFLD) has grown from a relatively unknown disease to the most common cause of chronic liver disease in the world.
Z. Younossi, F. Tacke, M. Arrese, Barjesh Chander Sharma, I. Mostafa, E. Bugianesi, V. Wai‐Sun Wong, Y. Yılmaz, J. George, Jian-Gao Fan, M. Vos   +10 more
semanticscholar   +1 more source

Angiopoietin-like protein as a novel marker for liver fibrosis in chronic hepatitis B patients with normal to minimally raised ALT

BMC Infectious Diseases, 2017
Background For hepatitis B patients who do not meet the treatment criteria recommended by guidelines, therapy decisions depend on hepatic histology.
Yongqiong Deng, Hong Zhao, Jiyuan Zhou, Linlin Yan, Guiqiang Wang, China HepB-Related Fibrosis Assessment Research Group   +5 more
doaj   +1 more source

Role of liensinine in sensitivity of activated macrophages to ferroptosis and in acute liver injury

Cell Death Discovery, 2023
Acute liver injury (ALI) is an acute inflammatory liver disease with a high mortality rate. Alternatively, activated macrophages (AAMs) have been linked to the inflammation and recovery of ALI.
Jing Li, Qi Huang, Minling Lv, Wenfeng Ma, Jialing Sun, Xin Zhong, Rui Hu, MengQing Ma, Zhiyi Han, Wei Zhang, Wenxing Feng, Xinfeng Sun, Xiaozhou Zhou   +12 more
doaj   +1 more source

A Rare Case of Gastric Perforation Secondary to Endoscopic Glue Injection for Gastric Varices

Journal of Digestive Endoscopy, 2021
Gastric perforation is very rare. Gastric perforation following endoscopic glue injection for gastric varices (GVs) in patients with portal hypertension (PHT) has not been documented till date. They are associated with significant morbidity and mortality.
Varun Khandagale, Sandesh Sharma, Pranav Raghuwanshi, Sanjay Kumar   +3 more
doaj   +1 more source

Housing-temperature reveals energy intake counter-balances energy expenditure in normal-weight, but not diet-induced obese, male mice

Communications Biology, 2022
The impact of ambient housing temperature on the interaction of energy intake, energy expenditure and glycemic control in normal and diet-induced obese mice is examined.
Linu Mary John, Natalia Petersen, Marina Kjærgaard Gerstenberg, Lola Torz, Kent Pedersen, Berit Østergaard Christoffersen, Rune Ehrenreich Kuhre   +6 more
doaj   +1 more source

Study on the Retreatment, Outcome, and Potential Predictors of Recurrence in Patients With Recurrence of Hepatitis B After Functional Cure

Frontiers in Immunology, 2022
BackgroundStudies about the retreatment and predictors for patients with hepatitis B recurrence after functional cure are rare. This study aimed to evaluate the effect of retreatment, outcome, and potential predictors of recurrence in patients with ...
Xiao Lin, Aixin Song, Junfeng Lu, Sujun Zheng, Zhongjie Hu, Lina Ma, Zhenhuan Cao, Hong Li, Yanhong Zheng, Shan Ren, Xinyue Chen   +10 more
doaj   +1 more source