Results 71 to 80 of about 12,541,927 (431)
Role of the Inflammasome in Liver Disease.
Annual Review of Pathology, 2021 The involvement of inflammasomes in the proinflammatory response observed in chronic liver diseases, such as alcohol-associated liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD), is widely recognized.
Marcelle de Carvalho Ribeiro, G. Szabo
semanticscholar +1 more source
BMC Medical Genomics, 2021 Background Although the effects of macrophages and CD8 T cell infiltration on clinical outcome have been widely reported, the association between immunity-associated gene with them for hepatocellular carcinoma (HCC) remains unclear. Materials and methods
Junyu Huo, Liqun Wu, Yunjin Zang
doaj +1 more source
Endothelial dysfunction in adolescents and young adults with nonalcoholic liver disease [PDF]
, 2019 Nonalcoholic liver disease is a global public health problem that increases cardiovascular morbidity and mortality in these patients. This paper discusses endothelial dysfunction among patients (adolescents and young adults) with nonalcoholic liver ...
Donoiu, Ionuț +6 more
core +1 more source
Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood. [PDF]
, 2016 Excess collagen synthesis (fibrogenesis) in the liver plays a causal role in the progression of nonalcoholic fatty liver disease (NAFLD). Methods are needed to identify patients with more rapidly progressing disease and to demonstrate early response to ...
Angel, Thomas E +16 more
core +1 more source
Gastroenterology, 2020 BACKGROUND & AIMS Biopsy-confirmed liver fibrosis is a prognostic factor for patients with non-alcoholic fatty liver disease (NAFLD). We performed a systematic review to quantify the prognostic value of fibrosis stage in patients with NAFLD and the ...
R. Taylor +17 more
semanticscholar +1 more source
Ferroptosis in liver disease: new insights into disease mechanisms
Cell Death Discovery, 2021 Characterized by excessive iron accumulation and lipid peroxidation, ferroptosis is a novel form of iron-dependent cell death, which is morphologically, genetically, and biochemically distinct from other well-known cell death.
Jing Wu +6 more
semanticscholar +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Novel Molecular Mechanisms in the Development of Non-Alcoholic Steatohepatitis. [PDF]
, 2016 Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in adults and children worldwide. NAFLD has become a severe health issue and it can progress towards a more severe form of the disease, the non-alcoholic ...
Feldstein, Ariel E, Povero, Davide
core +2 more sources
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Infectious Diseases and Therapy, 2020 Objectives This study aimed to observe the efficacy of corticosteroids in non-severe COVID-19 pneumonia. Methods A retrospective study based on propensity score matching was designed to explore the effects of corticosteroids.
Qiang Li +8 more
doaj +1 more source