Autophagy in non-alcoholic fatty liver disease and alcoholic liver disease
Liver Research, 2018 Autophagy is an evolutionarily conserved intracellular degradative function that is important for liver homeostasis. Accumulating evidence suggests that autophagy is deregulated during the progression and development of alcoholic and non-alcoholic liver ...
Bilon Khambu +4 more
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Frontiers in Medicine, 2022 Background:Non-alcoholic fatty liver disease (NAFLD) is a global health problem affecting more than a quarter of the entire adult population. Both monocytes and high-density lipoprotein cholesterol (HDL-C) were found to participate in the progression of ...
Liping Wang +8 more
doaj +1 more source
Postgraduate Medical Journal, 2000 Abstract Alcohol is a major cause of liver cirrhosis in the Western world and accounts for the majority of cases of liver cirrhosis seen in district general hospitals in the UK. The three most widely recognised forms of alcoholic liver disease are alcoholic fatty liver (steatosis), acute alcoholic hepatitis, and alcoholic cirrhosis.
K, Walsh, G, Alexander
openaire +5 more sources
Oral Pathogenic Bacteria and the Oral–Gut–Liver Axis: A New Understanding of Chronic Liver Diseases
Diagnostics, 2023 Liver diseases have long been a prevalent cause of morbidity and mortality, and their development and progression involve multiple vital organs throughout the body.
Yumeng Lei +6 more
doaj +1 more source
Subclinical versus advanced forms of alcohol-related liver disease: Need for early detection [PDF]
Clinical and Molecular Hepatology, 2023 Alcohol-related liver disease (ALD) consists of a wide spectrum of clinical manifestations and pathological features, ranging from asymptomatic patients to decompensated cirrhosis and hepatocellular carcinoma.
Concepción Gómez-Medina +3 more
doaj +1 more source
Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]
, 2020 In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco +4 more
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Endoplasmic reticulum stress and autophagy dysregulation in alcoholic and non-alcoholic liver diseases [PDF]
Clinical and Molecular Hepatology, 2020 Alcoholic and non-alcoholic liver diseases begin from an imbalance in lipid metabolism in hepatocytes as the earliest response. Both liver diseases share common disease features and stages (i.e., steatosis, hepatitis, cirrhosis, and hepatocellular ...
Yun Seok Kim, Sang Geon Kim
doaj +1 more source
Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis [PDF]
, 2020 Background A non-invasive method to grade the severity of steatohepatitis and liver fibrosis is magnetic resonance imaging (MRI) based corrected T1 (cT1).
Banerjee, R +25 more
core +3 more sources
The effect of 12 weeks regular physical activity and vitamin E in the treatment of non-alcoholic steatohepatitis: A pilot study [PDF]
, 2015 Background: Despite the prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH), there was no treatment has been proven to be effective in these common diseases.
Eslami, L. +5 more
core +7 more sources
Comparative Study on Serum Enzyme Levels in Cirrhosis of Liver and Alcoholic Liver Disease
Journal of Basic and Applied Research in Biomedicine, 2022 Patients with chronic liver diseases are asymptomatic or have only vague non-specific symptoms. Effective medical treatments for chronic liver disease (before cirrhosis is established) are becoming increasingly available and since abnormal LFTs may be ...
P Rjeshwari +3 more
doaj +2 more sources