Results 31 to 40 of about 651,421 (240)

Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases [PDF]

Endocrinology and Metabolism, 2019
The signaling network of the mitochondrial unfolded protein response (UPRmt) and mitohormesis is a retrograde signaling pathway through which mitochondria-to-nucleus communication occurs in organisms. Recently, it has been shown that the UPRmt is closely
Hyon-Seung Yi
doaj   +1 more source

Liver transplantation for alcoholic cirrhosis: Long term follow-up and impact of disease recurrence [PDF]

, 2001
Background. Alcoholic liver disease has emerged as a leading indication for hepatic transplantation, although it is a controversial use of resources. We aimed to examine all aspects of liver transplantation associated with alcohol abuse.
Andrea M. DiMartini, Anthony J. Demetris, Ashok Jain, Balan, Bassendine, Becker, Belle, Bellentani, Beresford, Beresford, Beresford, Berlakovich, Bernard, Bizollon, Blakolmer, Campbell, Chao, Christopher O.C. Bellamy, Conjeevaram, Cromie, Duvoux, Enomoto, Everhart, Everson, Fauerholdt, Ferrell, Forrest Dodson, Foster, Gane, Graziadei, Harrison, Hoofnagle, Howard, Iezzoni, Ishak, Jain, John J. Fung, Keeffe, Kenngott, Kris Ruppert, Kumar, Kyriacou, Lee, Levin, Levy, Lucey, Lucey, Lucey, Mendenhall, Michael Torbenson, Nabel, Neuberger, Neuberger, Neuberger, Osorio, Pageaux, Pappo, Pereira, Reed, Reich, Saunders, Schiff, Seitz, Sherlock, Shev, Starzl, Tang, Thomas E. Starzl, Tringali, Uchimura, Wiesner, Yates   +71 more
core   +1 more source

Ferroptosis in Chronic Liver Diseases: Opportunities and Challenges

Frontiers in Molecular Biosciences, 2022
Ferroptosis, an iron-dependent non-apoptotic cell death characterized by lipid peroxidation, is a cell death pathway discovered in recent years. Ferroptosis plays an important role in tumors, ischemia-reperfusion injury, neurological diseases, blood ...
Xiaoxi Zhou, Xiaoxi Zhou, Yadong Fu, Yadong Fu, Yadong Fu, Yadong Fu, Wei Liu, Wei Liu, Yongping Mu, Yongping Mu, Hua Zhang, Hua Zhang, Jiamei Chen, Jiamei Chen, Ping Liu, Ping Liu, Ping Liu   +16 more
doaj   +1 more source

Apoptosis and non-alcoholic fatty liver diseases

World Journal of Gastroenterology, 2018
The number of patients with nonalcoholic fatty liver diseases (NAFLD) including nonalcoholic steatohepatitis (NASH), has been increasing. NASH causes cirrhosis and hepatocellular carcinoma (HCC) and is one of the most serious health problems in the world.
T. Kanda, Shunichi Matsuoka, M. Yamazaki, Toshikatsu Shibata, K. Nirei, Hiroshi Takahashi, Tomohiro Kaneko, Mariko Fujisawa, Teruhisa Higuchi, H. Nakamura, Naoki Matsumoto, Hiroaki Yamagami, M. Ogawa, H. Imazu, K. Kuroda, M. Moriyama   +15 more
semanticscholar   +1 more source

Role of High-Mobility Group Box-1 in Liver Pathogenesis [PDF]

, 2019
High-mobility group box 1 (HMGB1) is a highly abundant DNA-binding protein that can relocate to the cytosol or undergo extracellular release during cellular stress or death. HMGB1 has a functional versatility depending on its cellular location.
Huda, Nazmul, Khambu, Bilon, Yan, Shengmin, Yin, Xiao-Ming   +3 more
core   +1 more source

Risk of liver dysfunction and non-alcoholic fatty liver diseases in people with hidradenitis suppurativa: A systematic review and meta-analysis of real-world evidences

Frontiers in Immunology, 2022
BackgroundTo date, evidences with high evidence-level evaluating the association between liver diseases and hidradenitis suppurativa was lacking. Given that inconsistency exists in some of the previous observational studies, evaluating the prevalence of ...
Shuo-Yan Gau, Shuo-Yan Gau, Yu-Ping Hsiao, Yu-Ping Hsiao, Wen-Chieh Liao, Kevin Sheng-Kai Ma, Kevin Sheng-Kai Ma, Kevin Sheng-Kai Ma, Meng-Che Wu, Meng-Che Wu, Meng-Che Wu   +10 more
doaj   +1 more source

A lupine (Lupinus angustifolious L.) peptide prevents non-alcoholic fatty liver disease in high-fat-diet-induced obese mice [PDF]

, 2020
Bioactive peptides are related to the prevention and treatment of many diseases. GPETAFLR is an octapeptide that has been isolated from lupine (Lupinus angustifolius L.) and shows anti-inflammatory properties.
Claro Cala, Carmen María, Grao Cruces, Elena, Lemus Conejo, Ana, Millán, Francisco, Millán-Linares, María del Carmen, Montserrat de la Paz, Sergio, Pedroche, Justo, Toscano, Rocío, Varela Pérez, Lourdes María   +8 more
core   +1 more source

Specificities of lipotoxicity of free fatty acids and cytokine profile in patients with chronic diffuse liver diseases

Regulatory Mechanisms in Biosystems, 2021
Non-alcoholic fatty liver disease is an important cause of global liver disease characterized by diffuse hepatocytes with hepatocellular ballooning, intrahepatic inflammation and progressive fibrosis.
V. I. Didenko, I. A. Klenina, О. M. Tatarchuk, O. I. Hrabovska, O. P. Petishko   +4 more
doaj   +1 more source

Disparities between research attention and burden in liver diseases: implications on uneven advances in pharmacological therapies in Europe and the USA [PDF]

, 2017
Effective oral therapies for hepatitis B and C have recently been developed, while there are no approved pharmacological therapies for alcoholic and non-alcoholic fatty liver diseases (ALD and NAFLD).
Barritt, A Sidney, Bataller, Ramon, Cabezas, Joaquin, Javaherian, Kavon, Lightbourne, Teisha G., Ndugga, Nambi, Verma, Neha   +6 more
core   +2 more sources

High serum N-terminal propeptide of procollagen type III concentration is associated with liver diseases

Gastroenterology Review, 2017
Introduction : N-terminal propeptide of procollagen type III (PIIINP) is generated during the synthesis of type III collagen. PIIINP can be measured in the serum as an indicator of liver fibrosis and cirrhosis.
Monika Gudowska, Ewa Gruszewska, Anatol Panasiuk, Bogdan Cylwik, Magdalena Swiderska, Robert Flisiak, Maciej Szmitkowski, Lech Chrostek   +7 more
doaj   +1 more source