Results 31 to 40 of about 205,862 (308)
Progress and Prospects of Non-Canonical NF-κB Signaling Pathway in the Regulation of Liver Diseases
Molecules, 2022 Non-canonical nuclear factor kappa B (NF-κB) signaling pathway regulates many physiological and pathological processes, including liver homeostasis and diseases.
Li Tao +3 more
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Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle [PDF]
, 2017 The estimates of global incidence and prevalence of non-alcoholic fatty liver disease (NAFLD) are worrisome, due to the parallel burden of obesity and its metabolic complications. Indeed, excess adiposity and insulin resistance represent two of the major
Chiesa, Claudio +4 more
core +2 more sources
Bacteriophage Prevents Alcoholic Liver Disease [PDF]
Cell, 2020 Alcoholic hepatitis is a severe alcohol-associated liver disease with minimal treatment options. A recent study by Duan et al. uncovers that the exotoxin-secreting gut bacterium Enterococcus faecalis is a critical contributor to alcoholic hepatitis.
Colakoglu, Melis +2 more
openaire +3 more sources
The Role of Nrf2 in Liver Disease: Novel Molecular Mechanisms and Therapeutic Approaches
Frontiers in Pharmacology, 2019 Oxidative stress and inflammation are the most important pathogenic events in the development and progression of liver diseases. Nuclear erythroid 2-related factor 2 (Nrf2) is the master regulator of the cellular protection via induction of anti ...
Dongwei Xu +6 more
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Alcoholic liver disease. Clinical example
Медицинский совет, 2020 Alcoholic liver disease (ALD) is one of the major liver diseases associated with high mortality rates. There are about 3 million alcohol-related deaths worldwide every year.
T. E. Polunina
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Medical Clinics of North America, 1989 Alcohol has been implicated in the genesis of liver disease for centuries. Significant progress has been made in our understanding of the pathogenesis of ALD. It is now apparent that both the consumption and the metabolism of alcohol promote the production of inflammatory mediators (cytokines) that result in hepatotoxicity and fibrogenesis.
openaire +3 more sources
Necroptosis in ischemia-reperfusion injury of lean and steatotic livers
Liver Research, 2019 Hepatic ischemia-reperfusion (IR) injury is a major complication during liver transplantation, liver resection, and other clinical situations. Increased hepatic IR injury in steatotic livers is a major reason for rejecting the use of steatotic livers for
Hua Sun +3 more
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Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease [PDF]
, 2014 Chronic abuse of alcohol leads to various histological abnormalities in the liver. These are conditions collectively known as alcoholic liver disease (ALD). Currently, ALD is considered to be one of the major causes of death worldwide.
Alisi, A., Ceccarelli, S, Nobili, V
core +1 more source
World Journal of Hepatology, 2012 Alcohol use disorders affect millions of individuals worldwide. Alcohol consumption is directly associated with liver disease mortality and accounts for elevated social and economic costs. Alcoholic liver disease (ALD) may take the form of acute involvement (alcoholic hepatitis) or chronic liver disease (steatosis, steatohepatitis, fibrosis and ...
Radan, Bruha +2 more
openaire +2 more sources
Advances in the concomitant chronic liver disease and colorectal cancer liver metastasis [PDF]
Waike lilun yu shijianLiver metastasis is a key factor contributing to the poor prognosis of patients with colorectal cancer (CRC), and chronic liver diseases promote the occurrence and development of CRC liver metastasis (CRLM) through various mechanisms such as altering the
YANG Yue, ZHAO Lei
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