Progress and Prospects of Non-Canonical NF-κB Signaling Pathway in the Regulation of Liver Diseases
Non-canonical nuclear factor kappa B (NF-κB) signaling pathway regulates many physiological and pathological processes, including liver homeostasis and diseases.
Li Tao +3 more
doaj +1 more source
Clinical features of alcoholic hepatitis in latinos and caucasians: A single center experience. [PDF]
AimTo study differences of presentation, management, and prognosis of alcoholic hepatitis in Latinos compared to Caucasians.MethodsWe retrospectively screened 876 charts of Caucasian and Latino patients who were evaluated at University of California ...
Durbin-Johnson, Blythe +3 more
core +1 more source
The Role of Nrf2 in Liver Disease: Novel Molecular Mechanisms and Therapeutic Approaches
Oxidative stress and inflammation are the most important pathogenic events in the development and progression of liver diseases. Nuclear erythroid 2-related factor 2 (Nrf2) is the master regulator of the cellular protection via induction of anti ...
Dongwei Xu +6 more
doaj +1 more source
Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle [PDF]
The estimates of global incidence and prevalence of non-alcoholic fatty liver disease (NAFLD) are worrisome, due to the parallel burden of obesity and its metabolic complications. Indeed, excess adiposity and insulin resistance represent two of the major
Chiesa, Claudio +4 more
core +2 more sources
Alcohol has been implicated in the genesis of liver disease for centuries. Significant progress has been made in our understanding of the pathogenesis of ALD. It is now apparent that both the consumption and the metabolism of alcohol promote the production of inflammatory mediators (cytokines) that result in hepatotoxicity and fibrogenesis.
openaire +3 more sources
Necroptosis in ischemia-reperfusion injury of lean and steatotic livers
Hepatic ischemia-reperfusion (IR) injury is a major complication during liver transplantation, liver resection, and other clinical situations. Increased hepatic IR injury in steatotic livers is a major reason for rejecting the use of steatotic livers for
Hua Sun +3 more
doaj +1 more source
Paediatric non-alcoholic fatty liver disease: impact on patients and mothers' quality of life [PDF]
Background: Non-alcoholic fatty liver disease (NAFLD) is one of the causes of fatty liver in adults and is currently the primary form of chronic liver disease in children and adolescents. However, the psychological outcome (i.e.
Armando, M +11 more
core +2 more sources
Advances in the concomitant chronic liver disease and colorectal cancer liver metastasis [PDF]
Liver metastasis is a key factor contributing to the poor prognosis of patients with colorectal cancer (CRC), and chronic liver diseases promote the occurrence and development of CRC liver metastasis (CRLM) through various mechanisms such as altering the
YANG Yue, ZHAO Lei
doaj +1 more source
Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease [PDF]
Chronic abuse of alcohol leads to various histological abnormalities in the liver. These are conditions collectively known as alcoholic liver disease (ALD). Currently, ALD is considered to be one of the major causes of death worldwide.
Alisi, A., Ceccarelli, S, Nobili, V
core +1 more source
Sex difference in the interaction of alcohol intake, hepatitis B virus, and hepatitis C virus on the risk of cirrhosis [PDF]
Background The joint effect of the interaction of alcohol intake, hepatitis B virus (HBV) and hepatitis C virus (HCV) on the risk of cirrhosis is still unexplored because a large sample size is required for this investigation.
Almasio, Piero Luigi +11 more
core +6 more sources

