Results 51 to 60 of about 651,421 (240)
Advances in Alcoholic Liver Disease [PDF]
This special issue reflects on multiple factors/mechanisms involved in the pathogenesis of ALD. Alcoholic liver injury is known to cause a broad range of liver abnormalities. Alcohol is primarily metabolized in the hepatocyte leading to increased secretion of inflammatory mediators, which, in turn, activate and/or influence the response of the ...
Kusum K. Kharbanda+3 more
openaire +4 more sources
Alcoholic hepatitis (AH) is a clinical manifestation on the spectrum of alcoholic liver diseases related to alcohol consumption. The mildest of these diseases is fatty liver, which can progress to AH and then lead to cirrhosis with continual alcohol use.
Naqvi, Syed, Padkins, Mitchell
core +1 more source
Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis [PDF]
Background A non-invasive method to grade the severity of steatohepatitis and liver fibrosis is magnetic resonance imaging (MRI) based corrected T1 (cT1).
Banerjee, R+25 more
core +3 more sources
The effect of 12 weeks regular physical activity and vitamin E in the treatment of non-alcoholic steatohepatitis: A pilot study [PDF]
Background: Despite the prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH), there was no treatment has been proven to be effective in these common diseases.
Eslami, L.+5 more
core +7 more sources
Alcoholic disease: Liver and beyond [PDF]
The harmful use of alcohol is a worldwide problem. It has been estimated that alcohol abuse represents the world's third largest risk factor for disease and disability; it is a causal factor of 60 types of diseases and injuries and a concurrent cause of at least 200 others.
ROCCO, ALBA+4 more
openaire +2 more sources
Microbiota and hepatic diseases
The data on the existing knowledge in the field of intestinal microbiota influence on human diseases were presented, in particular, non-alcoholic fat liver disease, alcoholic liver disease, inflammatory intestinal diseases and infectious gastrointestinal
T. E. Polunina
doaj
A study conducted 15-year ago showed that only 13.5% of chronic alcoholics developed alcohol-induced liver damage, which misled some people to believe a lack of relationship between the amount of alcohol and the occurrence of liver disease. However, it is true that a significant correlation exists between per capita consumption and the prevalence of ...
openaire +2 more sources
Adiponectin has recently been shown to be a promising candidate for the treatment of obesity-associated metabolic syndromes. Replenishment of recombinant adiponectin in mice can decrease hyperglycemia, reverse insulin resistance, and cause sustained ...
A. Xu+5 more
semanticscholar +1 more source
Bile acid receptors FXR and TGR5 signaling in fatty liver diseases and therapy.
Bile acid synthesis is the most significant pathway for catabolism of cholesterol and for maintaining whole body cholesterol homeostasis. Bile acids are physiological detergents that absorb, distribute, metabolize and excrete nutrients, drugs and ...
J. Chiang, Jessica M. Ferrell
semanticscholar +1 more source
Biomimetic Approach to Elucidate the Role of Microenvironment in Regulating Cell Communications in Liver Diseases [PDF]
Liver is a complex organ but often underappreciated for its functions to remove toxins and fight infection in the body. Despite the ongoing prevalence of patients contracting chronic liver diseases, coupled with a global healthcare investment of ...
Moeun, Youra
core +1 more source