Results 51 to 60 of about 651,421 (240)

Advances in Alcoholic Liver Disease [PDF]

open access: yesInternational Journal of Hepatology, 2012
This special issue reflects on multiple factors/mechanisms involved in the pathogenesis of ALD. Alcoholic liver injury is known to cause a broad range of liver abnormalities. Alcohol is primarily metabolized in the hepatocyte leading to increased secretion of inflammatory mediators, which, in turn, activate and/or influence the response of the ...
Kusum K. Kharbanda   +3 more
openaire   +4 more sources

Alcoholic hepatitis [PDF]

open access: yes, 2018
Alcoholic hepatitis (AH) is a clinical manifestation on the spectrum of alcoholic liver diseases related to alcohol consumption. The mildest of these diseases is fatty liver, which can progress to AH and then lead to cirrhosis with continual alcohol use.
Naqvi, Syed, Padkins, Mitchell
core   +1 more source

Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis [PDF]

open access: yes, 2020
Background A non-invasive method to grade the severity of steatohepatitis and liver fibrosis is magnetic resonance imaging (MRI) based corrected T1 (cT1).
Banerjee, R   +25 more
core   +3 more sources

The effect of 12 weeks regular physical activity and vitamin E in the treatment of non-alcoholic steatohepatitis: A pilot study [PDF]

open access: yes, 2015
Background: Despite the prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH), there was no treatment has been proven to be effective in these common diseases.
Eslami, L.   +5 more
core   +7 more sources

Alcoholic disease: Liver and beyond [PDF]

open access: yesWorld Journal of Gastroenterology, 2014
The harmful use of alcohol is a worldwide problem. It has been estimated that alcohol abuse represents the world's third largest risk factor for disease and disability; it is a causal factor of 60 types of diseases and injuries and a concurrent cause of at least 200 others.
ROCCO, ALBA   +4 more
openaire   +2 more sources

Microbiota and hepatic diseases

open access: yesЛечащий Врач, 2021
The data on the existing knowledge in the field of intestinal microbiota influence on human diseases were presented, in particular, non-alcoholic fat liver disease, alcoholic liver disease, inflammatory intestinal diseases and infectious gastrointestinal
T. E. Polunina
doaj  

Alcoholic Liver Disease [PDF]

open access: yesThe Korean Journal of Gastroenterology, 2009
A study conducted 15-year ago showed that only 13.5% of chronic alcoholics developed alcohol-induced liver damage, which misled some people to believe a lack of relationship between the amount of alcohol and the occurrence of liver disease. However, it is true that a significant correlation exists between per capita consumption and the prevalence of ...
openaire   +2 more sources

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice.

open access: yesJournal of Clinical Investigation, 2003
Adiponectin has recently been shown to be a promising candidate for the treatment of obesity-associated metabolic syndromes. Replenishment of recombinant adiponectin in mice can decrease hyperglycemia, reverse insulin resistance, and cause sustained ...
A. Xu   +5 more
semanticscholar   +1 more source

Bile acid receptors FXR and TGR5 signaling in fatty liver diseases and therapy.

open access: yesAmerican Journal of Physiology - Gastrointestinal and Liver Physiology, 2020
Bile acid synthesis is the most significant pathway for catabolism of cholesterol and for maintaining whole body cholesterol homeostasis. Bile acids are physiological detergents that absorb, distribute, metabolize and excrete nutrients, drugs and ...
J. Chiang, Jessica M. Ferrell
semanticscholar   +1 more source

Biomimetic Approach to Elucidate the Role of Microenvironment in Regulating Cell Communications in Liver Diseases [PDF]

open access: yes, 2023
Liver is a complex organ but often underappreciated for its functions to remove toxins and fight infection in the body. Despite the ongoing prevalence of patients contracting chronic liver diseases, coupled with a global healthcare investment of ...
Moeun, Youra
core   +1 more source

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