Results 51 to 60 of about 201,743 (308)

Iron and steatohepatitis. [PDF]

, 2012
As the main iron storage site in the body and the main source of the iron-regulatory hormone, hepcidin, the liver plays a pivotal role in iron homeostasis.
Amato, Anstee, Argo, Bekri, Bridle, Bugianesi, Chapman, Chung, Cohen, Corradini, Day, Deugnier, Dongiovanni, Duane, Fabbrini, Facchini, Fernández-Real, Fletcher, Friedman, Ganne-Carrié, Gao, Harrison-Findik, Harrison-Findik, Ji, Kim, Kohgo, Kotronen, Kowdley, Lin, Mendler, Moirand, Nahon, Nelson, Nemeth, Nishina, Ohtake, Pietrangelo, Pietrangelo, Pietrangelo, Pietrangelo, Pietrangelo, She, Sorrentino, Tavill, Tsukamoto, Valenti, Valenti, Valenti, Vecchi, Zimmermann   +49 more
core   +1 more source

Liver transplantation for alcoholic liver disease [PDF]

Clinical Liver Disease, 2013
Alcoholism is a disease of remission and relapse. A lapse in abstinence tends to be viewed as a failure to commit to abstinence, and an acknowledged relapse may lead to the patient's removal from the liver transplant list; however, such a relapse may actually offer insight into alcoholism.
Patrizia, Burra, Michael R, Lucey
openaire   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Clinico-Biochemical Correlation to Histological Findings in Alcoholic Liver Disease: A Single Centre Study from Eastern India [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Alcoholism is a health problem not only in developed countries but also in developing countries. Cirrhosis due to alcohol is a common cause of death among individuals abusing alcohol.
Sayantan Ray, Dibbendhu Khanra, Nikhil Sonthalia, Supratip Kundu, Kaushik Biswas, Arunansu Talukdar, Manjari Saha, Himel Bera   +7 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Persistent deficiency of mucosa-associated invariant T (MAIT) cells during alcohol-related liver disease

Cell & Bioscience, 2021
Background Alcohol-related liver disease (ALD) is a major cause of chronic liver diseases. Inflammatory response is a basic pathological feature of ALD.
Yujue Zhang, Yuanyuan Fan, Wei He, Yi Han, Huarui Bao, Renjun Yang, Bingbing Wang, Derun Kong, Hua Wang   +8 more
doaj   +1 more source

Role of silymarin in the management of deranged liver function in non-alcoholic steatohepatitis: a case report

Drugs in Context, 2023
Non-alcoholic fatty liver disease is one of the main causes of elevated liver enzymes and chronic liver disease worldwide. It ranges from steatosis to steatohepatitis, leading to cirrhosis and related liver dysfunction.
Yeong Yeh Lee, Vincent Tee
doaj   +1 more source

Studies of liver phosphorylase in hepatic injuries. I. Alteration in enzyme activity [PDF]

, 1978
Phosphorylase activities (total and a form) were determined in the livers of experimental hepatic injuries with carbon tetrachloride or galactosamine and the livers of patients with liver diseases.
Kobayashi, Michio
core   +1 more source

Microbiota, Liver Diseases, and Alcohol

Microbiology Spectrum, 2017
ABSTRACTBeing overweight and obesity are the leading causes of liver disease in Western countries. Liver damage induced by being overweight can range from steatosis, harmless in its simple form, to steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Alcohol consumption is an additional major cause of liver disease.
Gerard, Philippe, Cassard-Doulcier, Anne-Marie, Perlemuter, Gabriel   +2 more
openaire   +4 more sources

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source