Results 11 to 20 of about 11,864,187 (263)
Liver diseases: epidemiology, causes, trends and predictions
Signal Transduction and Targeted TherapyAs a highly complex organ with digestive, endocrine, and immune-regulatory functions, the liver is pivotal in maintaining physiological homeostasis through its roles in metabolism, detoxification, and immune response.
Jia Xiao, Jinhang Gao, Haiyuan Shen
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Regulation and functional roles of chemokines in liver diseases
Nature Reviews Gastroenterology and Hepatology, 2021 Inflammation is a major contributor to the pathogenesis of almost all liver diseases. Low-molecular-weight proteins called chemokines are the main drivers of liver infiltration by immune cells such as macrophages, neutrophils and others during an ...
Sheng Cao +2 more
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International Journal of Molecular Sciences, 2019 The rapid scientific interest in gut microbiota (GM) has coincided with a global increase in the prevalence of infectious and non-infectivous liver diseases.
Miloš Korac +2 more
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The Role of Oxidative Stress and Antioxidants in Liver Diseases
International Journal of Molecular Sciences, 2015 A complex antioxidant system has been developed in mammals to relieve oxidative stress. However, excessive reactive species derived from oxygen and nitrogen may still lead to oxidative damage to tissue and organs.
, Yibin Feng, Ning Wang
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Hepatology, 2021 This is the first American Association for the Study of Liver Diseases (AASLD) Practice Guidance on the management of malnutrition, frailty, and sarcopenia in patients with cirrhosis.
J. Lai +6 more
semanticscholar +1 more source
Hepatology, 2023 This commentary discusses how clinicians and various stakeholders can utilize the recently published American Association for the Study of Liver Diseases nonalcoholic fatty liver disease (AASLD NAFLD) Practice Guidance in light of the change in the ...
F. Kanwal +3 more
semanticscholar +1 more source
Mitochondrial alterations in fatty liver diseases.
Journal of Hepatology, 2022 Fatty liver diseases increasingly arise from common metabolic diseases, but also from xenobiotics and excessive alcohol use. Despite different etiology, they share several similarities regarding their toxic effects on hepatic mitochondrial functionality ...
B. Fromenty, M. Roden
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Journal of Diabetes Research, 2022 Background. Chronic hepatitis B cirrhosis is often accompanied by glucose metabolism disorder, and intestinal microbiota was closely related to both cirrhosis and diabetes.
Xiu Sun +4 more
doaj +1 more source
Mitochondrial dysfunction: A promising therapeutic target for liver diseases
Genes and Diseases, 2023 The liver is an important metabolic and detoxification organ and hence demands a large amount of energy, which is mainly produced by the mitochondria.
Ping Chen +6 more
semanticscholar +1 more source
Fenofibrate in primary sclerosing cholangitis; a randomized, double‐blind, placebo‐controlled trial
Pharmacology Research & Perspectives, 2022 Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with no medical treatment proven to improve survival and postpone liver transplantation. Previous studies have shown the effectiveness of fibrates in primary biliary cholangitis.
Behzad Hatami +5 more
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