Results 21 to 30 of about 11,864,187 (263)
Autophagy in liver diseases: A review
Molecular Aspects of Medicine, 2021 The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid synthesis as well as drug/xenobiotic metabolism and detoxification.
Hui Qian +6 more
semanticscholar +1 more source
Microorganisms, 2021 Mucosal-associated invariant T (MAIT) cells are a subset of T lymphocytes expressing a semi-invariant T-cell receptor (TCR) present as TCR Vα7.2-Jα33 in humans and TCR Vα19-Jα33 in mice.
Yoseph Asmelash Gebru +9 more
doaj +1 more source
Endoplasmic Reticulum Stress in Liver Diseases
Hepatology, 2022 The endoplasmic reticulum (ER) is an intracellular organelle that fosters the correct folding of linear polypeptides and proteins, a process tightly governed by the ER-resident enzymes and chaperones.
Amir Ajoolabady +6 more
semanticscholar +1 more source
BMC Cancer, 2023 Background Thermal therapy induces an immune response in patients with hepatocellular carcinoma (HCC), but the dynamic characteristics of the natural killer (NK) cell immune response post-thermal ablation remain unclear.
Hai-Yan Wang +6 more
doaj +1 more source
The Nrf2 Pathway in Liver Diseases
Frontiers in Cell and Developmental Biology, 2022 Oxidative stress is the leading cause of most liver diseases, such as drug-induced liver injury, viral hepatitis, and alcoholic hepatitis caused by drugs, viruses, and ethanol.
Jiaming Zhou, Q. Zheng, Zhi H. Chen
semanticscholar +1 more source
Cigarette Smoking and Liver Diseases.
Journal of Hepatology, 2022 Cigarette smoking is a preventable risk factor of premature morbidity and mortality. Smoking history is observed in approximately 40% of patients with liver disease. A growing number of studies have investigated the potential impact of smoking in chronic
D. Martí-Aguado +2 more
semanticscholar +1 more source
Periodontitis, chronic liver diseases, and the emerging oral‐gut‐liver axis
Periodontology 2000, 2022 The liver carries out a wide range of functions ranging from the control of metabolites, nutrient storage, and detoxification to immunosurveillance. While inflammation is essential for the tissue remodeling and maintenance of homeostasis and normal liver
E. Albuquerque‐Souza, S. E. Sahingur
semanticscholar +1 more source
The Role of Gut-Derived Lipopolysaccharides and the Intestinal Barrier in Fatty Liver Diseases
Journal of Gastrointestinal Surgery, 2021 Hepatosteatosis is the earliest stage in the pathogenesis of nonalcoholic fatty (NAFLD) and alcoholic liver disease (ALD). As NAFLD is affecting 10–24% of the general population and approximately 70% of obese patients, it carries a large economic burden ...
Lingxuan An +11 more
semanticscholar +1 more source
Oxidative Stress, Genomic Integrity, and Liver Diseases
Molecules, 2022 Excess reactive oxygen species production and free radical formation can lead to oxidative stress that can damage cells, tissues, and organs. Cellular oxidative stress is defined as the imbalance between ROS production and antioxidants.
Nanthini Sadasivam +3 more
semanticscholar +1 more source
Hematological Malignancies and HBV Reactivation Risk: Suggestions for Clinical Management
Viruses, 2019 It is well known that hepatitis B virus reactivation (HBVr) can occur among patients undergoing treatment for hematological malignancies (HM). The evaluation of HBVr risk in patients undergoing immunosuppressive treatments is a multidimensional process ...
Alessandra Zannella +2 more
doaj +1 more source