Results 21 to 30 of about 11,653,388 (315)

The convergent application of metabolites from Avena sativa and gut microbiota to ameliorate non-alcoholic fatty liver disease: a network pharmacology study

Journal of Translational Medicine, 2023
Background Non-alcoholic fatty liver disease (NAFLD) is a serious public health issue globally, currently, the treatment of NAFLD lies still in the labyrinth.
Ki-Kwang Oh, Sang-Jun Yoon, Su-Been Lee, Sang Youn Lee, Haripriya Gupta, Raja Ganesan, Satya Priya Sharma, Sung-Min Won, Jin-Ju Jeong, Dong Joon Kim, Ki-Tae Suk   +10 more
doaj   +1 more source

Pediatric liver diseases: current challenges and future perspectives [PDF]

, 2015
Chronic liver diseases in children represent a rising problem with significant effects on public health. In fact, several pediatric liver diseases are precursors of adult chronic hepatopathies, cirrhosis and hepatocellular carcinoma.
Alisi, Anna, Alterio, Arianna, Della Corte, Claudia, Mosca, Antonella, Nobili, Valerio, Vania, Andrea   +5 more
core   +1 more source

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]

, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco, Francis, Heather, Kennedy, Lindsey, Kundu, Debjyoti, Meadows, Vik   +4 more
core   +1 more source

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

Hepatology, 2018
This guidance provides a data-supported approach to the diagnostic, therapeutic, and preventive aspects of NAFLD care. A "Guidance" document is different from a "Guideline." Guidelines are developed by a multidisciplinary panel of experts and rate the ...
N. Chalasani, Z. Younossi, J. Lavine, M. Charlton, K. Cusi, M. Rinella, S. Harrison, E. Brunt, A. Sanyal   +8 more
semanticscholar   +1 more source

Gut microbiome and metabolome signatures in liver cirrhosis-related complications [PDF]

Clinical and Molecular Hepatology
Background/Aims Shifts in the gut microbiota and metabolites are interrelated with liver cirrhosis progression and complications. However, causal relationships have not been evaluated comprehensively.
Satya Priya Sharma, Haripriya Gupta, Goo-Hyun Kwon, Sang Yoon Lee, Seol Hee Song, Jeoung Su Kim, Jeong Ha Park, Min Ju Kim, Dong-Hoon Yang, Hyunjoon Park, Sung-Min Won, Jin-Ju Jeong, Ki-Kwang Oh, Jung A Eom, Kyeong Jin Lee, Sang Jun Yoon, Young Lim Ham, Gwang Ho Baik, Dong Joon Kim, Ki Tae Suk   +19 more
doaj   +1 more source

Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases

Clinical Liver Disease, 2019
and Scope This guidance provides a data-supported approach to the diagnosis, staging, and treatment of patients diagnosed with hepatocellular carcinoma (HCC). A guidance document is different from a guideline.
J. Marrero, L. Kulik, C. Sirlin, A. Zhu, R. Finn, M. Abecassis, L. Roberts, J. Heimbach   +7 more
semanticscholar   +1 more source

Pharmacological properties of baicalin on liver diseases: a narrative review

Pharmacological Reports, 2021
Baicalin is the main active component of Scutellaria baicalensis, widely used in traditional Chinese medicine thanks to its various pharmacological effects, such as anti-tumor, anti-inflammatory, and antibacterial properties, as well as cardiovascular ...
Jin-yu Yang, Min Li, Chengliang Zhang, Dong Liu   +3 more
semanticscholar   +1 more source

Label-free metabolic imaging of non-alcoholic-fatty-liver-disease (NAFLD) liver by volumetric dynamic optical coherence tomography [PDF]

Biomed. Opt. Express 13 (2022) 4071-4086, 2022
Label-free metabolic imaging of non-alcoholic fatty liver disease (NAFLD) mouse liver is demonstrated ex vivo by dynamic optical coherence tomography (OCT). The NAFLD mouse is a methionine choline-deficient (MCD)-diet model, and two mice fed MCD diet for 1 and 2 weeks are involved in addition to a normal-diet mouse.
arxiv   +1 more source

Bile acid receptors FXR and TGR5 signaling in fatty liver diseases and therapy.

American Journal of Physiology - Gastrointestinal and Liver Physiology, 2020
Bile acid synthesis is the most significant pathway for catabolism of cholesterol and for maintaining whole body cholesterol homeostasis. Bile acids are physiological detergents that absorb, distribute, metabolize and excrete nutrients, drugs and ...
J. Chiang, Jessica M. Ferrell
semanticscholar   +1 more source

A Transformer-Based Deep Learning Approach for Fairly Predicting Post-Liver Transplant Risk Factors [PDF]

J Biomed Inform. 2024 Jan;149:104545, 2023
Liver transplantation is a life-saving procedure for patients with end-stage liver disease. There are two main challenges in liver transplant: finding the best matching patient for a donor and ensuring transplant equity among different subpopulations. The current MELD scoring system evaluates a patient's mortality risk if not receiving an organ within ...
arxiv   +1 more source