Results 21 to 30 of about 1,677,984 (258)

Csi-let-7a-5p delivered by extracellular vesicles from a liver fluke activates M1-like macrophages and exacerbates biliary injuries

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Infection with liver flukes (such as Clonorchis sinensis) can induce severe biliary injuries. But we don’t know how it happens. Here, we find that a microRNA Csi-let-7a-5p delivered by extracellular vesicles from C.
Chao Yan, Qian Zhou, Jing Wu, Na Xu, Ying Du, Jing Li, Ji-xin Liu, S. Koda, Beibei Zhang, Qian Yu, Hui-min Yang, Xiangyang Li, Bo Zhang, Yinhai Xu, Jia-xu Chen, Zhongdao Wu, Xing-Quan Zhu, R. Tang, K. Zheng   +18 more
semanticscholar   +1 more source

Human liver flukes [PDF]

The Lancet Gastroenterology & Hepatology, 2017
Liver fluke infections occur in people worldwide. In some low-income regions, a combination of ecological, agricultural, and culinary factors leads to a very high prevalence of infection but, in higher-income regions, infections are uncommon. Infection is associated with substantial morbidity and several liver fluke species are recognised as biological
Harrington, David, Lamberton, Poppy H.L., McGregor, Alastair   +2 more
openaire   +2 more sources

Knockout of liver fluke granulin, Ov-grn-1, impedes malignant transformation during chronic infection with Opisthorchis viverrini

bioRxiv, 2021
Infection with the food-borne liver fluke Opisthorchis viverrini is the principal risk factor for cholangiocarcinoma (CCA) in the Mekong Basin countries of Thailand, Lao PDR, Vietnam, Myanmar and Cambodia.
Sujittra Chaiyadet, S. Tangkawattana, M. Smout, W. Ittiprasert, V. Mann, Raksawan Deenonpoe, Patpicha Arunsan, A. Loukas, P. Brindley, T. Laha   +9 more
semanticscholar   +1 more source

Body condition scores, fluke intensity, liver pathology, and carcass quality of different dairy cattle genotypes infected with Fasciola species at high throughput abattoirs in South Africa

Parasitology Research, 2022
Milk is an essential commodity whose demand far exceeds supply. However, dairy animal productivity is constantly hampered by parasitic diseases such as fasciolosis, affecting milk production. Despite the negative impact of liver fluke on milk production,
Zuko Mpisana, I. Jaja, C. Byaruhanga, M. C. Marufu   +3 more
semanticscholar   +1 more source

Epithelial–Mesenchymal Transition in Liver Fluke-Induced Cholangiocarcinoma

Cancers, 2021
Simple Summary Parasitic infection remains a health threat in many countries. Liver flukes, parasitic flatworms endemic to southeast and east Asia, cause bile duct inflammation and are major risk factors of bile duct cancer (cholangiocarcinoma).
K. Sawanyawisuth, G. Sashida, Guojun Sheng   +2 more
semanticscholar   +1 more source

Prevalence and gross pathology of liver fluke in macropods cohabiting livestock farms in north eastern NSW, Australia, and diagnosis using cELISA

International Journal for Parasitology: Parasites and Wildlife, 2021
Liver fluke (Fasciola hepatica) is a parasite of herbivores including wildlife. Macropods, such as Eastern grey kangaroo (Macropus giganteus) and Common wallaroo (Osphranter robustus), are frequently observed sharing grazing sites with domestic livestock.
Jane Lamb, Emma Doyle, Jamie Barwick, Michael Chambers, Lewis Kahn   +4 more
doaj   +1 more source

Anthelmintic Activity of Antioxidants: In Vitro Effects on the Liver Fluke Opisthorchis felineus

Pathogens, 2021
Currently, molecular parasitologists are searching for new agents against trematodiases. Redox metabolism is important for parasites as far as long-lived adult parasites inside a mammalian host are exposed to redox challenges.
V. Mordvinov, D. Ponomarev, Y. Pakharukov, M. Pakharukova   +3 more
semanticscholar   +1 more source

Role of laminin and cognate receptors in cholangiocarcinoma cell migration

Cell Adhesion & Migration, 2021
Extensive desmoplasia in cholangiocarcinoma (CCA) is associated with tumor aggressiveness, indicating a need for further understanding of CCA cell–matrix interaction.
Kittiya Islam, Parichut Thummarati, Pakkanun Kaewkong, Banchob Sripa, Tuangporn Suthiphongchai   +4 more
doaj   +1 more source

Aberrant GLUT1 Expression Is Associated With Carcinogenesis and Progression of Liver Fluke-associated Cholangiocarcinoma

In Vivo, 2021
Background/Aim: Glucose transporter 1 (GLUT1) has been demonstrated to be overexpressed in various cancer tissues and play a significant role on growth, metastasis, and apoptosis in cancer cells.
Ubonrat Thamrongwaranggoon, Sakkarn Sangkhamanon, Wunchana Seubwai, Paksiree Saranaruk, U. Cha'on, S. Wongkham   +5 more
semanticscholar   +1 more source

Prevalence of liver fluke (Fasciola hepatica) in wild Red Deer (Cervus elaphus): coproantigen ELISA is a practicable alternative to faecal egg counting for surveillance in remote populations [PDF]

, 2016
Red deer (Cervus elaphus) are hosts of liver fluke (Fasciola hepatica); yet, prevalence is rarely quantified in wild populations. Testing fresh samples from remote regions by faecal examination (FE) can be logistically challenging; hence, we appraise ...
Craine, Alexandra, French, Andrew S., Gibb, Stuart W., Gordon-Gibbs, Danielle K., Mitchell, Gillian, Shaw, David, Skuce, Philip J., Taggart, Mark A., Zadoks, Ruth N.   +8 more
core   +6 more sources