Results 101 to 110 of about 494,521 (299)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Liver Function Tests

Bristol medico-chirurgical journal (1883)
Lala V, Zubair M, Minter DA.
europepmc   +2 more sources

Improvement in liver functions tests for chronic hepatitis C patients treated with direct acting antivirals

, 2019
Mohamed Mahmoud El Kassas, Mohamed Alboraie, Mohammad E. Soliman, Ahmed F. Sherief, Inas Moaz, Adel El Tahan, Mohamed F. M. Ibrahim, Nermeen Abdeen, Sameera Ezzat   +8 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The assessment of function, histopathological changes, and oxidative stress in liver tissue due to ionizing and non-ionizing radiations

Caspian Journal of Internal Medicine, 2020
Background: Compared to past decades, humans are exposed to rapidly increasing levels of radiofrequency electromagnetic radiations (RF-EMF). Despite numerous studies, the biological effects of human exposure to different levels of RF-EMF are not fully ...
Sajad Borzoueisileh, Ali Shabestani Monfared, Hossein Ghorbani, S. M. J. Mortazavi, Mohsen Shafiee, Amir Hossein Doustimotlagh, Ebrahim zabihi, Mehdi Pouramir, Fatemeh Niksirat   +8 more
doaj  

Liver function tests at admission as marker of severity and prognosis in COVID-19 patients - A retrospective analysis. [PDF]

J Family Med Prim Care, 2023
Himral P, Bhawani R, Bhardwaj M, Sharma N.   +3 more
europepmc   +1 more source

Efficacy and safety of hepano tablet in liver disorder patients with abnormal liver function test: A randomized active controlled prospective clinical study

, 2017
Satyendra Kumar, Arun Kumar Gupta, Meenakshi Revadekar, Sagar More, Abhay Kulkarni, SunilS Borkar   +5 more
openalex   +1 more source

Liver Function Tests in Survivors of Haemolytic Disease of The Newborn [PDF]

, 1963
Taylor Bird, A. J. Cassells‐Smith, Weldon J. Walker   +2 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source