Results 151 to 160 of about 508,172 (252)

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Association between insulin and liver function tests, liver disease and cirrhosis in population-based cohorts with long term follow-up. [PDF]

open access: yesWorld J Hepatol
Schult A   +7 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

A machine learning-based framework for predicting metabolic syndrome using serum liver function tests and high-sensitivity C-reactive protein. [PDF]

open access: yesSci Rep
Behkamal B   +9 more
europepmc   +1 more source

Severe Acetaminophen Toxicity From the Use of Oxycodone-Acetaminophen With Normal Liver Function Tests and a Completely Asymptomatic Course of Hospitalization. [PDF]

open access: yesACG Case Rep J, 2023
Haider MA   +7 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Transient Elevation of Liver Function Tests and Bilirubin Levels After Laparoscopic Cholecystectomy. [PDF]

open access: yesMedicina (Kaunas)
Giakoustidis A   +9 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Decoding platelet function in liver cirrhosis: A shift from quantity to quality [PDF]

open access: yesClinical and Molecular Hepatology
Vibhuti Jakhmola   +2 more
doaj   +1 more source

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