Results 171 to 180 of about 527,738 (310)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Modulation of Blood Lead Level and Liver Function Tests in Iranian Opium Users. [PDF]

Int J Prev Med
Eskandarion MR, Kohansal M, Chavoshi M, Forutan M, Ghorbani R, Heidari F, Azizian R, Norouzi M, Nazparvar B, Tabasi M, Akhgari M.   +10 more
europepmc   +1 more source

Impact of obesity on liver function tests: is nonalcoholic fatty liver disease the only player? A review article. [PDF]

Porto Biomed J, 2023
El-Eshmawy MM.
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Determination of reference intervals for common liver function tests among healthy adults. [PDF]

Sci Rep
Abbas AB, Yahya A, Aloqab Z, AlHudhaifi A, Alateef AA, Morshed A, Qasem A, Al-Awlaqi M, Alshahari S, Mohammed N, Mohammed K.   +10 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Liver function tests among children with moderate acute malnutrition: A secondary analysis of a randomized trial from Burkina Faso. [PDF]

J Pediatr Gastroenterol Nutr
Winther CL, Helt TW, Fabiansen C, Frikke-Schmidt R, Filteau S, Briend A, Michaelsen KF, Friis H, Christensen VB.   +8 more
europepmc   +1 more source

Associations between Rest-Activity Rhythms and Liver Function Tests: The US National Health and Nutrition Examination Survey, 2011-2014. [PDF]

Clocks Sleep, 2023
Yeung CHC, Bauer C, Xiao Q.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

The association between liver function tests abnormalities and type 2 diabetes mellitus patients in Saudi Arabia: a cross-sectional study. [PDF]

Front Clin Diabetes Healthc
Mehyar N, Alhajeri Z, Alosaimi M, Alanazi Z, Alanazi A, Abusaris R.   +5 more
europepmc   +1 more source