Results 51 to 60 of about 504,752 (301)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Correlation between liver function tests and metabolic syndrome in hepatitis-free elderly

Journal of Medical Sciences, 2015
Background: We aimed to investigate the relationship between liver function tests (LFTs) and metabolic syndrome (MetS) as several studies have shown positive correlations between some of the LFTs, including alanine aminotransferase (ALT) and γ-glutamyl ...
Hung-Sheng Shang, Bing-Heng Yang, Cherng-Lih Perng, Sheng-Hue Tang, Chien-Ming Lin, Jin-Biou Chang   +5 more
doaj   +1 more source

Evaluation of Liver function Tests in Normotensive and Hypertensive pregnancy. [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2017
Pregnancy-induced hypertension (PIH) is responsible for significant maternal and prenatal morbidity, liver function affected by this disease. Liver function tests ( LFTs ), namely S.ALP, S.AST, S.ALT, Albumin, Bilirubin and prothrombin time were ...
Marwa Ibrahim Salman
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Evaluation of the Liver and Pancreatic Functions in Patients with Alcohol-Related Sialadenosis – A Case Control Study

Journal of Pharmacy and Bioallied Sciences
Background: Sialadenosis or sialosis is the asymptomatic symmetric parotid enlargement without inflammation or neoplasia, seen in persons 30–69 years old, often related to chronic alcohol use, endocrine disorders, and obesity. Materials and Methods: This
E Elavarasi, Vinothini Gunasekaran, Mohan Thirumal, R Balaji Subramaniyan, Ravi David Austin, S Thirumalai   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Correlation Between Haematological Parameters, Kidney Function Tests and Liver Function Tests in Plasmodium Falciparum and Vivax Malaria [PDF]

Walawalkar International Medical Journal, 2017
: Malaria remains a major cause of morbidity and mortality in India. Plasmodium falciparum remains the main culprit although cases with vivax malaria are on the rise.
Mitul Chhatriwala, Anup Nillawar, Sandip Patil, Dinesh Bure   +3 more
doaj  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The effects of N-acetylcysteine on hepatic function during isoflurane anaesthesia for laparoscopic surgery patients

Indian Journal of Anaesthesia, 2011
Introduction: Although most general anaesthesia procedures are performed without any complications, volatile agents may have adverse effects on various living systems. This study aims to compare the antioxidant effects of isoflurane and N-acetylcysteine (
Serbülent Gökhan Beyaz, Birgul Yelken, Güngor Kanbak   +2 more
doaj   +1 more source