Results 21 to 30 of about 2,360,733 (398)

Colorectal liver metastases [PDF]

Postgraduate Medical Journal, 1996
Summary Each year in the UK, between 12-14,000 people develop liver metastases from colorectal cancer. These metastases will contribute to the death of the patient in about 80% of cases. Treatments aimed at these tumours are best administered when the tumour is small.
D, Burke, T G, Allen-Mersh
openaire   +2 more sources

Cryotherapy for liver metastases [PDF]

Cochrane Database of Systematic Reviews, 2011
The liver is affected by two of the most common groups of malignant tumours: primary liver tumours and liver metastases from colorectal carcinoma. Liver metastases are significantly more common than primary liver cancer and long-term survival rates reported for patients after radical surgical treatment is approximately 50%.
Bała, Małgorzata, Riemsma, Robert P., Wolff, Robert, Pędziwiatr, Michał, Mituś, Jerzy, Storman, Dawid, Świerz, Mateusz J., Kleijnen, Jos   +7 more
openaire   +5 more sources

Liver resection for non-colorectal, non-carcinoid, non-sarcoma metastases: a multicenter study. [PDF]

PLoS ONE, 2015
The role of liver resection for non-colorectal, non-neuroendocrine, non-sarcoma (NCNNNS) metastases is ill-defined. This study aimed to examine the oncologic outcomes of liver resection in such patients.A retrospective analysis of liver resection for ...
Guillaume Martel, Jeff Hawel, Janelle Rekman, Kristopher P Croome, Kimberly Bertens, Fady K Balaa, Roberto Hernandez-Alejandro   +6 more
doaj   +1 more source

Prognostic characteristics and clinical response to immunotherapy targeting programmed cell death 1 for patients with advanced gastric cancer with liver metastases

Frontiers in Immunology, 2022
BackgroundThe specific efficacy of immunotherapy for patients with liver metastases of gastric cancer is unclear. This study set out to explore the treatment response and related prognostic factors for patients with liver metastases of gastric cancer ...
Huayuan Liang, Zhiwei Li, Zhicheng Huang, Chaorui Wu, Yaopeng Qiu, Yanrui Liang, Xinhua Chen, Fengping Li, Zhou Xu, Guoxin Li, Hao Liu, Liying Zhao   +11 more
doaj   +1 more source

The effect of routine lymphadenectomy of the hepatic basin on the duration of the liver resection due to colorectal carcinoma metastases [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. Today, lymphatic metastases are only a relative contraindication for the surgical treatment of colorectal carcinoma (CRC). The aim of this study was to evaluate the effect of routine lymphadenectomy of the hepatic basin on the duration of
Basarić Dragan D., Soldatović Ivan, Lekić Nebojša, Đorđević Vladimir, Đurašić Ljubomir, Micev Marjan   +5 more
doaj   +1 more source

PD-L1 expression in liver metastasis: its clinical significance and discordance with primary tumor in colorectal cancer

Journal of Translational Medicine, 2020
Background The outcomes of immune checkpoint inhibitors in cancer patients with liver metastases are poor, which may be related to a different tumor microenvironment in liver metastases from primary tumors.
Xiao-Li Wei, Xuan Luo, Hui Sheng, Yun Wang, Dong-Liang Chen, Jia-Ning Li, Feng-Hua Wang, Rui-Hua Xu   +7 more
doaj   +1 more source

Can localised 19F magnetic resonance spectroscopy pharmacokinetics of 5FU in colorectal metastases predict clinical response? [PDF]

, 2010
Background 5-Fluorouracil remains widely used in colorectal cancer treatment more than 40 years after its development. 19F magnetic resonance spectroscopy can be used in vivo to measure 5FU’s half-life and metabolism to cytotoxic fluoronucleotides ...
Griffiths, John R., Ladroue, Christophe, Lofts, F, Lofts, Fiona, Griffiths, JR, John R. Griffiths, Marion Stubbs, Stubbs, Marion, Franklyn A. Howe, Fiona Lofts, McIntyre, DJ, Ladroue, C, Howe, FA, Howe, Franklyn A., McIntyre, Dominick J. O., Dominick J. O. McIntyre, Stubbs, M, Christophe Ladroue   +17 more
core   +1 more source

Colorectal liver metastases: Current management and future perspectives

World Journal of Clinical Oncology, 2020
The liver is the commonest site of metastatic disease for patients with colorectal cancer, with at least 25% developing colorectal liver metastases (CRLM) during the course of their illness.
Jack Martin, A. Petrillo, E. Smyth, N. Shaida, Samir A Khwaja, H. Cheow, A. Duckworth, P. Heister, R. Praseedom, A. Jah, A. Balakrishnan, S. Harper, S. Liau, V. Kosmoliaptsis, E. Huguet   +14 more
semanticscholar   +1 more source

Phosphorylated transducer and activator of transcription-3 (pSTAT3) immunohistochemical expression in paired primary and metastatic colorectal cancer

Translational Oncology, 2021
Background: Signal Transducer and Activator of Transcription-3 (STAT3) mediates cellular functions. We assessed the IHC expression of phosphorylated STAT3 (pSTAT3) in paired primary tumors and liver metastases in patients with advanced stage colorectal ...
Esmeralda C. Marginean, Joanna Gotfrit, Horia Marginean, Daniel W. Yokom, Justin J. Bateman, Manijeh Daneshmand, Shelly Sud, Allen M. Gown, Derek Jonker, Timothy Asmis, Rachel A. Goodwin   +10 more
doaj   +1 more source

Autofluorescence-Raman Spectroscopy for Ex Vivo Mapping Colorectal Liver Metastases and Liver Tissue

, 2023
Introduction: Identifying colorectal liver metastases (CRLM) during liver resection could assist in achieving clear surgical margins, which is an important prognostic variable for both disease-free and overall survival.
Dusanjh, Palminder Kaur, Harwood, Andrew, Mukherjee, Abhik, Dhanwant Gomez, Palminder Kaur Dusanjh, Abhik Mukherjee, Boitor, Radu, Christopher Corden, Ioan Notingher, Radu Boitor, Corden, Christopher, Notingher, Ioan, Gomez, Dhanwant, Andrew Harwood   +13 more
core   +1 more source