Results 41 to 50 of about 2,360,733 (398)

Comprehensive analysis of cutaneous and uveal melanoma liver metastases

Journal for ImmunoTherapy of Cancer, 2020
Background The profound disparity in response to immune checkpoint blockade (ICB) by cutaneous melanoma (CM) and uveal melanoma (UM) patients is not well understood. Therefore, we characterized metastases of CM and UM from the same metastatic site (liver)
E. Hoefsmit, E. Rozeman, Trieu-My Van, P. Dimitriadis, O. Krijgsman, J. Conway, I. Pires da Silva, J. E. van der Wal, S. Ketelaars, Kaspar Bresser, A. Broeks, R. Kerkhoven, J. Reeves, S. Warren, P. Kvistborg, R. Scolyer, E. Kapiteijn, D. Peeper, G. Long, T. Schumacher, C. Blank   +20 more
semanticscholar   +1 more source

Correlation between recurrence-free survival and overall survival after upfront surgery for resected colorectal liver metastases

, 2023
Background The role of recurrence-free survival (RFS) as a valid surrogate endpoint for overall survival (OS) in patients who underwent upfront surgery for colorectal liver metastases remains uncertain.
Takeuchi, J, Joint Comm Liver Metastases Survey, [missing], Kataoka, K, Ito, K, Kanemitsu, Y, Hasegawa, K, Ajioka, Y, Endo, I, Beppu, N, Ceelen, Wim, Ikeda, M, Takahashi, K   +11 more
core   +1 more source

Colorectal cancer liver metastases – a population-based study on incidence, management and survival

BMC Cancer, 2018
Colorectal cancer (CRC) is a leading cause of cancer-associated deaths with liver metastases developing in 25–30% of those affected. Previous data suggest a survival difference between right- and left-sided liver metastatic CRC, even though left-sided ...
J. Engstrand, H. Nilsson, C. Strömberg, E. Jonas, J. Freedman   +4 more
semanticscholar   +1 more source

Identifying CT-Based Risk Factors Associated with Synchronous Liver Metastases in Colorectal Cancer

대한영상의학회지, 2017
Purpose: The aim of this study was to determine the radiologic risk factors of colorectal cancer (CRC) with synchronous liver metastases. Materials and Methods: A total of 197 patients with CRC who had a visible tumor on contrast-enhanced ...
Cho Rong Seo, Seung Joon Choi, Hyung Sik Kim   +2 more
doaj   +1 more source

Chemotherapy-associated liver morphological changes in hepatic metastases (CALMCHeM) [PDF]

, 2023
PURPOSETo review imaging findings in chemotherapy-associated liver morphological changes in hepatic metastases (CALMCHeM) on computed tomography (CT)/magnetic resonance imaging (MRI) and its association with tumor burden.METHODSWe performed a ...
Kristina T. Flicek, Zhen Wang, Matthew C. Pope, Sudhakar K. Venkatesh, Christine O. Menias, Candice W. Bolan, Neema J. Patel, Michael C. Olson   +7 more
core   +1 more source

The varied clonal trajectory of liver and lung metastases of colorectal cancer

Advances in Cancer Biology - Metastasis
Background: The liver and lungs are the most common sites of colorectal cancer (CRC) metastases. Their involvement can take five different clinical scenarios: lung metastases only, liver metastases only, lung metastases before liver metastases, liver ...
Ofer N. Gofrit, Ben Gofrit, S. Nahum Goldberg, Aron Popovtzer, Jacob Sosna, Ayala Hubert   +5 more
doaj   +1 more source

Angiopoietin-2 blockade suppresses growth of liver metastases from pancreatic neuroendocrine tumors by promoting T cell recruitment

The Journal of Clinical Investigation, 2023
Improving the management of metastasis in pancreatic neuroendocrine tumors (PanNETs) is critical, as nearly half of patients with PanNETs present with liver metastases, and this accounts for the majority of patient mortality. We identified angiopoietin-2
Eunhyeong Lee, Sophie O’Keefe, Alessandra Leong, Ha-Ram Park, Janani Varadarajan, Subrata Chowdhury, Shannon Hiner, Sungsoo Kim, Anahita Shiva, Richard A. Friedman, Helen Remotti, Tito Fojo, Hee Won Yang, Gavin Thurston, Minah Kim   +14 more
doaj   +1 more source

The impact of pulmonary metastasectomy in patients with previously resected colorectal cancer liver metastases. [PDF]

PLoS ONE, 2017
BACKGROUND:40-50% of patients with colorectal cancer (CRC) will develop liver metastases (CRLM) during the course of the disease. One third of these patients will additionally develop pulmonary metastases. METHODS:137 consecutive patients with CRLM, were
Armin Wiegering, Johannes Riegel, Johanna Wagner, Volker Kunzmann, Johannes Baur, Thorsten Walles, Ulrich Dietz, Stefan Loeb, Christoph-Thomas Germer, Ulrich Steger, Ingo Klein   +10 more
doaj   +1 more source

What defines 'cure' after liver resection for colorectal metastases? Results after 10 years of follow-up

, 2010
Background: During the last two decades, resection of colorectal liver metastases (CLM) in selected patients has become the standard of care, with 5-year survival rates of 25-58%.
Parks, Rowan W.; id_orcid, Aldrighetti, Luca, Garden, O. James, Parks, Rowan W., Bodingbauer, Martin, Wigmore, Stephen J., Castillo, Federico, Ferla, Gianfranco, Pulitano, Carlo   +8 more
core   +1 more source

Radiofrequency Ablation for Colorectal Cancer Liver Metastases: Outcomes and Prognostic Factors Associated with Survival

, 2023
Background: To determine the long-term outcomes of radiofrequency ablation with respect to overall survival, disease-free survival, and complications in patients with colorectal cancer liver metastases.
Okan Akhan, Türkmen Çiftçi, Devrim Akıncı, ÇİFTÇİ, Türkmen Turan, Emre Ünal, ÜNAL, EMRE, METİN, Yavuz, Seray Akçalar, AKINCI, Devrim, AKHAN, Okan, Akçalar, Seray, Yavuz Metin   +11 more
core   +1 more source