Results 61 to 70 of about 2,360,733 (398)

Bevacizumab Plus mFOLFOX6 Versus mFOLFOX6 Alone as First-Line Treatment for RAS Mutant Unresectable Colorectal Liver-Limited Metastases: The BECOME Randomized Controlled Trial.

Journal of Clinical Oncology, 2020
PURPOSE To assess the effects of bevacizumab plus modified fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) as first-line treatment of RAS mutant unresectable colorectal liver metastases.
W. Tang, L. Ren, Q. Ye, Ye Wei, G. He, Q. Lin, Xiaoying Wang, Ming-Liang Wang, F. Liang, Yuehong Cui, Tianshu Liu, Jianming Xu   +11 more
semanticscholar   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Evaluation of peri-tumoral vessels surrounding colorectal liver metastases after intravenous injection of extruded magnetoliposomes in rats: correlation with 3t mri and histopathology

Journal of the Belgian Society of Radiology, 2005
Background: Magnetoliposomes have pronounced signal-enhancing effect on T1-weighted (T1w) images of the liver using qualitative analysis which may be benefical for demonstrating peritumoral vasculature.
K Coenegrachts, J van Werven, L ter Beek, Z Mzallassi, M Bögels, Th van Gulik, I Van Den Berghe, A Nederveen, J Stoker, H Rigauts, S Soenen, M De Cuyper   +11 more
doaj   +1 more source

Liver metastases and the efficacy of immune checkpoint inhibitors in advanced lung cancer: A systematic review and meta-analysis

Frontiers in Oncology, 2022
BackgroundLiver metastasis is the most common type of lung cancer metastasis, and is a significant prognostic factor in lung cancer. However, the effect of liver metastases on the efficacy of immune checkpoint inhibitors (ICIs) remains inconsistent and ...
Handai Xia, Wengang Zhang, Yuqing Zhang, Xiaoling Shang, Yanguo Liu, Xiuwen Wang   +5 more
doaj   +1 more source

Radioembolization treatment for liver metastases

, 2017
The liver is an organ that, due to vascularisation and functions, is prone to metastases. Most liver metastases are observed in cases of gastrointestinal cancers in: stomach, colon, gallbladder, and bile ducts.
Joanna Kiszka, Bożenna Karczmarek-Borowska   +1 more
core   +1 more source

Whole liver CT texture analysis to predict the development of colorectal liver metastases-A multicentre study [PDF]

, 2017
Objectives: CT texture analysis has shown promise to differentiate colorectal cancer patients with/ without hepatic metastases. Aim: To investigate whether whole-liver CT texture analysis can also predict the development of colorectal liver metastases ...
Rao, Sheng-Xiang, Janneke B. Houwers, Stefano Trebeschi, Geerard L. Beets, Alfons G.H. Kessels, Beets, Geerard L., Houwers, Janneke B., Doenja M.J. Lambregts, Verhoef, Cornelis, Lambregts, Doenja M. J., Roald S. Schnerr, Thywissen, Thomas, Beckers, Rianne C. J., Schnerr, Roald S., Trebeschi, Stefano, Monique Maas, Cornelis H. Dejong, Rianne C.J. Beckers, Dejong, Cornelis H., Kessels, Alfons G. H., Beets-Tan, Regina G. H., Thomas Thywissen, Regina G.H. Beets-Tan, Maas, Monique, Sheng-Xiang Rao, Cornelis Verhoef   +25 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Complete remission of multiple liver metastases with only partial response of the primary rectal cancer after neoadjuvant chemotherapy

Surgical Case Reports, 2020
Background Colorectal cancer is commonly diagnosed among the Japanese population, and various strategies in treating the colorectal liver metastasis have been introduced over the years.
Satomi Miura, Kyoji Ito, Nobuyuki Takemura, Fuminori Mihara, Tomomichi Kiyomatsu, Norihiro Kokudo   +5 more
doaj   +1 more source