Results 61 to 70 of about 1,127,916 (265)

Vascular disorders of the liver: recommendations from the Italian Association for the Study of the Liver (AISF) ad hoc committee. [PDF]

, 2011
This review summarizes the document elaborated by the Italian Association for the Study of the Liver (AISF) ad hoc committee "Vascular disorders of the liver" on the primary circulatory liver diseases, which include Budd-Chiari syndrome, obstruction of ...
Riggio O, Sacerdoti D, Senzolo M, Primignani M, Italian Association for the Study of the Liver AISF ad hoc committee Vascular disorders of the liver, SACERDOTI, DAVID   +5 more
core   +1 more source

Surgical treatment of colorectal cancer metastases [PDF]

Scripta Medica, 2020
Background/Aim: Colorectal metastatic liver tumours are the most common secondary liver tumours. During the life of patients with colorectal tumorous, this liver metastases will develop either synchronously or metachronously in half of the patients ...
Škrbić Velimir, Simatović Milan, Janjić Goran, Šaran Dalibor   +3 more
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Imaging Related To Transplantation For Colorectal Liver Metastases

, 2019
In this thesis patients who underwent liver transplantation (LT) for unresectable colorectal liver metastases were studied (SECA study). Lifelong immunosuppression following LT is necessary to prevent organ rejection and the general perception is that ...
Grut, Harald
core   +1 more source

Liver manipulation causes hepatocyte injury and precedes systemic inflammation in patients undergoing liver resection. [PDF]

, 2007
Contains fulltext : 51690.pdf (Publisher’s version ) (Closed access)BACKGROUND: Liver failure following liver surgery is caused by an insufficient functioning remnant cell mass.
Derikx, J.P.M., Peters, Wilbert H M, Poll, M.C. van de, Buurman, Wim A, Roelofs, H.M., Wigmore, S.J., Dejong, Cornelis H C, Roelofs, H.M.J., Derikx, Joep P M, Buurman, W.A., van de Poll, M., van de Poll, Marcel C G, Wigmore, Stephen J, Roelofs, Hennie M J, Dejong, C.H., Peters, W.H.M.   +15 more
core   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Epidemiology of liver metastases

, 2020
Aims: The objectives of this study were to (1) characterize the epidemiology of liver metastases at the time of primary cancer diagnosis (synchronous liver metastases), (2) characterize the incidence trends of synchronous liver metastases from 2010−2015 ...
Stoltzfus, Kelsey C., Trifiletti, Daniel M., Horn, Samantha R., Gusani, Niraj J., Chen, Hanbo, Zaorsky, Nicholas G., Lehrer, Eric J., Dawson, Laura A., Sharma, Navesh K., Tchelebi, Leila   +9 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Semi-automatic 3D-volumetry of liver metastases from neuroendocrine tumors to improve combination therapy with 177Lu-DOTATOC and 90Y-DOTATOC [PDF]

, 2016
PURPOSEPatients with neuroendocrine tumors (NET) often present with disseminated liver metastases and can be treated with a number of different nuclides or nuclide combinations in peptide receptor radionuclide therapy (PRRT) depending on tumor load and ...
Tim Holland-Letz, Walter Mier, Jan Moltz, Clemens Kratochwil, Hans-Ulrich Kauczor, Peter Choyke, Uwe Haberkorn, Frederik L. Giesel, Matthaeus Cieciera   +8 more
core   +1 more source

Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival

BMC Gastroenterology, 2008
Background The tumour suppressor phosphatase and tensin homolog (PTEN) is an important negative regulator of cell-survival signaling. To evaluate the correlation between PTEN expression and clinicopathological characteristics of colorectal cancer ...
Funahashi Hitoshi, Takahashi Hiroki, Wakasugi Takehiro, Matsuo Yoichi, Ma Jiachi, Ochi Nobuo, Yasuda Akira, Sawai Hirozumi, Sato Mikinori, Takeyama Hiromitsu   +9 more
doaj   +1 more source