Results 51 to 60 of about 1,127,916 (265)
Outcome after resection of Adrenocortical Carcinoma liver metastases: a retrospective study
BMC Cancer, 2017 Background Metastatic Adrenocortical Carcinoma (ACC) is a rare malignancy with a poor 5-year-survival rate (
Johannes Baur +11 more
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundLiver metastasis is the most common type of lung cancer metastasis, and is a significant prognostic factor in lung cancer. However, the effect of liver metastases on the efficacy of immune checkpoint inhibitors (ICIs) remains inconsistent and ...
Handai Xia +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Development of A Computer-Aided Detection (CAD) Tool For Contrast Micro Computed Tomography Imaging In Diagnosing Liver Metastases [PDF]
, 2012 High morbidity of metastatic tumors in the liver has been observed in several different types of cancers. Liver failure from metastases is one of the primary causes of death in these patients.
Peck, Anderson Steadham
core
Evaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: A multicenter study [PDF]
, 2016 Background/Aim: The Kyushu Study Group of Clinical Cancer (KSCC) previously reported the safety and efficacy of neoadjuvant chemotherapy with mFOLFOX6 + bevacizumab for H2/H3 liver metastases of colorectal cancer.
Takatsuki, Mitsuhisa +14 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Superparamagnetic Iron Oxide (SPIO)-enhanced Liver MR Imaging with Ferucarbotran [PDF]
, 2006 Die Superparamagnetic Iron Oxides (SPIO)-verstärkte MRT der Leber wird als sinnvolle präoperative diagnostische Methode mit einer hohen Sensitivität und Spezifität für die Detektion von fokalen Leberläsionen angewendet.
Namkung, Sook
core +1 more source
Surgical Case Reports, 2023 Background The rate of residual liver recurrence after the resection of colorectal liver metastases is high, and most cases recur within 5 years of the initial hepatectomy. Here, we report two cases of residual liver recurrence after radical resection of
Shotaro Yagi +11 more
doaj +1 more source
The evolving role of radiation therapy as treatment for liver metastases
Journal of the National Cancer Center, 2022 Liver metastases occur commonly in many solid malignancies. With advances in systemic therapies and increased life expectancy, the role of using local therapies in oligo-metastases is rapidly increasing.
Khalid Alrabiah +4 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source