Results 1 to 10 of about 349,758 (166)

Liver Metastasis in Cancer: Molecular Mechanisms and Management

MedComm
Liver metastasis is a leading cause of mortality from malignant tumors and significantly impairs the efficacy of therapeutic interventions. In recent years, both preclinical and clinical research have made significant progress in understanding the ...
Wenchao Xu, Jia Xu, Jianzhou Liu, Nanzhou Wang, Li Zhou, Junchao Guo   +5 more
doaj   +1 more source

Lipid Nanoparticles-Based Therapy in Liver Metastasis Management: From Tumor Cell-Directed Strategy to Liver Microenvironment-Directed Strategy

International Journal of Nanomedicine, 2023
Yuhan Wang,1 Zhenyu Yin,1 Lei Gao,1 Bin Ma,1 Jianming Shi,1 Hao Chen2 1Lanzhou University Second Hospital, Lanzhou, 730030, People’s Republic of China; 2Department of Surgical Oncology, Key Laboratory of the Digestive System Tumors of Gansu Province ...
Wang Y, Yin Z, Gao L, Ma B, Shi J, Chen H   +5 more
doaj  

Construction of a nomogram model based on biomarkers for liver metastasis in non‐small cell lung cancer

Thoracic Cancer
Background Patients with non‐small cell lung cancer (NSCLC) with liver metastasis have a poor prognosis, and there are no reliable biomarkers for predicting disease progression.
Tian Zhang, Yajuan Zhang, Yunfeng Ni, Xiaohui Jia, Yanlin Li, Ziyang Mao, Panpan Jiang, Xiaolan Fu, Min Jiao, Lili Jiang, Wenjuan Wang, Hui Guo, Ying Zan, Mengjie Liu   +13 more
doaj   +1 more source

Mechanical Force‐Induced cGAS Activation in Carcinoma Cells Facilitates Splenocytes into Liver to Drive Metastasis

Advanced Science
Liver metastasis is the main cause of cancer‐related mortality. During the metastasis process, circulating carcinoma cells hardly pass through narrow capillaries, leading to nuclear deformation.
Xurui Zhang, Na Huang, Yanhua Mu, Haiyan Chen, Mengchen Zhu, Shaoying Zhang, Pengfei Liu, Hailong Zhang, Huan Deng, Keping Feng, Qi Shang, Xi Liu, Chen Zhang, Mengjiao Shi, Lan Yang, Jin Sun, Guangyao Kong, Jing Geng, Shemin Lu, Zongfang Li   +19 more
doaj   +1 more source

Risk factors of liver metastasis from advanced pancreatic adenocarcinoma: a large multicenter cohort study

World Journal of Surgical Oncology, 2017
Background Clinical prognostic parameters of liver metastasis from pancreatic adenocarcinoma have not been specifically identified.This study is to explore the risk factors of liver metastasis in advanced pancreatic adenocarcinoma (PDAC) patients in ...
Dong S., Wang L., Guo Y. B., Ying H. F., Shen X. H., Meng Z. Q., Chen Hao, Chen Q. W., Li Z. S.   +8 more
doaj   +1 more source

Predictive Value of Immune Inflammation Combined with Liver Function Hematological Indicators for Metastasis of Colorectal Cancer

Zhongliu Fangzhi Yanjiu
ObjectiveTo explore the predictive value of immune inflammation combined with liver function hematological indicators for the metastasis of colorectal cancer.
Xuelei CHU, Chen AN, Lingze XI, Hongting XIE, Mingtong ZONG, Peng XUE, Shijie ZHU   +6 more
doaj   +1 more source

The role of microRNAs in colorectal liver metastasis: Important participants and potential clinical significances

Tumor Biology, 2017
Colorectal cancer is one of the most common cancers in the world, and liver metastasis is the leading direct cause of cancer-related deaths in colorectal cancer.
Dongxu Wang, Jie Liu, Tingting Huo, Yaowen Tian, Lei Zhao   +4 more
doaj   +1 more source

Liver transplantation for unresectable colorectal liver metastasis.

Hepatobiliary surgery and nutrition, 2013
The rapid progression in the development of liver transplantation during the last decade is largely attributed by the standardization of operative techniques (1,2) and advances in the pharmacokinetics of immunosuppressive therapy (3). Such improvements in the perioperative management have rendered liver transplantation a safer operation and in turn ...
openaire   +3 more sources

Case Report: Mimicking benignity: hepatic sinusoidal metastasis masquerading as diffuse liver disease in small cell lung cancer

Frontiers in Oncology
BackgroundSmall cell lung cancer is extremely aggressive. Although liver metastasis is common, cases of diffuse intra-sinusoidal metastasis leading to liver failure and death are quite rare.Case presentationThis paper reports a case of a 58-year-old male
Lujiao Chen, Lulin Chen, Jianfeng Yang, Minxia Yang   +3 more
doaj   +1 more source

Prevention of liver metastasis via the pharmacological suppression of AMIGO2 expression in tumor cells

Scientific Reports
AMIGO2 adheres to liver endothelium and induces liver metastasis. We revealed that genetically altering AMIGO2 expression in tumor cells affects their liver metastatic potential, depending on the AMIGO2 expression level.
HeeKyung Seong, Yusuke Kanda, Runa Izutsu, Jumond P. Jehung, Junichi Hamada, Mitsuhiko Osaki, Koji Okamoto, Futoshi Okada   +7 more
doaj   +1 more source