Results 161 to 170 of about 1,906,831 (271)

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes.

British Journal of Clinical Pharmacology, 1998
V. Eagling, J. Tjia, D. Back
semanticscholar   +1 more source

Stability studies of β-Amino- and β-Hydroxy difluoromethyl ketones in rat serum and rat liver microsomes. [PDF]

Bioorg Med Chem Lett
Islam B, Kreusel KE, Sulochana SP, Nguyen AL, Sowaileh MF, Khatri HR, Griffin MH, Leara DA, Colby DA.   +8 more
europepmc   +1 more source

Effects of chronic cirrhosis induced by intraperitoneal thioacetamide injection on the protein content and Michaelis-Menten kinetics of cytochrome P450 enzymes in the rat liver microsomes. [PDF]

Basic Clin Pharmacol Toxicol, 2023
Chandrashekar DV, DuBois BN, Rashid M, Mehvar R.   +3 more
europepmc   +1 more source

A preliminary exploration of liver microsomes and PBPK to uncover the impact of CYP3A4/5 and CYP2C19 on tacrolimus and voriconazole drug-drug interactions. [PDF]

Sci Rep
Zhao YC, Zhang YK, Gao W, Liu HY, Xiao CL, Hou JJ, Li JK, Zhang BK, Xiang DX, Sandaradura I, Yan M.   +10 more
europepmc   +1 more source

When Cofactors Aren't X Factors: Functional Groups That Are Labile in Human Liver Microsomes in the Absence of NADPH. [PDF]

ACS Med Chem Lett, 2022
Landry ML, Trager R, Broccatelli F, Crawford JJ.   +3 more
europepmc   +1 more source

Identification and Characterization of Cannabichromene's Major Metabolite Following Incubation with Human Liver Microsomes. [PDF]

Metabolites
Ward AM, Shokati T, Klawitter J, Klawitter J, Nguyen V, Kozell L, Abbas AI, Jones D, Christians U.   +8 more
europepmc   +1 more source

Metabolism of a Selective Serotonin and Norepinephrine Reuptake Inhibitor Duloxetine in Liver Microsomes and Mice. [PDF]

Drug Metab Dispos, 2022
Qin X, Hakenjos JM, MacKenzie KR, Barzi M, Chavan H, Nyshadham P, Wang J, Jung SY, Guner JZ, Chen S, Guo L, Krishnamurthy P, Bissig KD, Palmer S, Matzuk MM, Li F.   +15 more
europepmc   +1 more source

Protein targets of reactive electrophiles in human liver microsomes.

Chemical Research in Toxicology, 2007
Nah-Young Shin, Qinfeng Liu, Sheryl L. Stamer, D. Liebler   +3 more
semanticscholar   +1 more source

Berberine and Metabolic Dysfunction‐Associated Steatotic Liver Disease: Hope or Hype?

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
Ruth Nona, Eric Kalo
wiley   +1 more source

Physcion inhibition of CYP2C9, 2D6 and 3A4 in human liver microsomes. [PDF]

Pharm Biol
Liu L, Sun S, Li X.
europepmc   +1 more source