Results 191 to 200 of about 154,170 (305)

Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury

, 2020
Yu-Hsuan Lin, Shuyuan Zhang, Min Zhu, Tianshi Lu, Kenian Chen, Zhuoyu Wen, Shidan Wang, Guanghua Xiao, Danni Luo, Yuemeng Jia, Lin Li, Malcolm MacConmara, Yujin Hoshida, Amit G. Singal, Adam C. Yopp, Tao Wang, Hao Zhu   +16 more
openalex   +2 more sources

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

The role of Toll-like receptors in liver regeneration after partial hepatectomy. [PDF]

Prz Gastroenterol
Dritsas S, Frountzas M, Schizas D, Mulita F, Katsimpoulas M, Gkolfakis P, Lidoriki I, Karavokyros I, Liolis E, Missiakos E, Liakakos T, Kapelouzou A.   +11 more
europepmc   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

Intrahepatic Lymphangiogenesis Is Associated with Early Post-Hepatectomy Liver Regeneration, in Part via IL-6/STAT3 Signaling. [PDF]

Int J Med Sci
Xie S, Fan X, Liu Y, Li H, Zhou C, Guo C, Tang X, Ming Y, Zhang P.   +8 more
europepmc   +1 more source

Neutrophil and macrophage crosstalk might be a potential target for liver regeneration

Yiyuan Chen, Yijie Yang, Jinjiao Lu, Huan Chen, Zhixiong Shi, Xiaodong Wang, Nan Xu, Xiao Xu, Shuai Wang   +8 more
openalex   +1 more source

Surgical Stress and Liver Response: Injury, Regeneration, and Protection [PDF]

Michitaka Ozaki, Sanae Haga
openalex   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Biagio Palmisano, Silvia Franco, Roberta Angelini, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +14 more
wiley   +1 more source

LECT2 promotes liver regeneration across developmental stages by activating the ADAM10-NOTCH signaling pathway. [PDF]

Hepatol Commun
Zhang H, Wang W, Gao Y, Qian Y, Xu W, Yin H, Qiu Q, Zhang L, Zhu S, Li X, Wu Z, Zuo L, Wang J, Tang H, Hu H, Wei Y, Xu F, Chen J, Cao F, Xu H.   +19 more
europepmc   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source