Results 21 to 30 of about 357,211 (306)
Gut and Liver, 2009 Liver transplantation has become a lifesaving procedure for patients who have chronic end-stage liver disease and acute liver failure. The satisfactory outcome of liver transplantation has led to insufficient supplies of deceased donor organs, particularly in East Asia.
Moon, Deok-Bog, Lee, Sung-Gyu
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Cell Death and Disease, 2023 Multidrug resistance is a major challenge in treating advanced hepatocellular carcinoma (HCC). Although recent studies have reported that the multidrug resistance phenotype is associated with abnormal DNA methylation in cancer cells, the epigenetic ...
Xiao-Jun Guo +17 more
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Pediatric Liver Transplantation
Clinics in Liver Disease, 2022 Liver transplantation (LT) for children results in excellent short- and long-term patient and graft survival. LT is a lifesaving procedure in children with acute or chronic liver disease, hepatic tumors, and select genetic metabolic diseases in which it can significantly improve quality of life.
Sara Kathryn, Smith, Tamir, Miloh
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Journal of Hematology & Oncology, 2021 Background Immune checkpoint blockade resistance narrows the efficacy of cancer immunotherapies, but the underlying mechanism remains elusive. Delineating the inherent mechanisms of anti-PD1 resistance is important to improve outcome of patients with ...
Jia-Cheng Lu +14 more
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Current Opinion in Gastroenterology, 2005 Liver transplantation continues to change as we further define appropriate criteria for allocation and utilization of this scarce resource. The following review highlights new trends and ideas in this evolving field.Although the model for end-stage renal disease (MELD) scoring system appears to fairly accurately predict mortality while waiting for ...
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Cell Death Discovery, 2022 Hepatocellular carcinoma (HCC) is one of the most serious malignant cancers and has a high fatality rate. However, clinical strategies for the effective treatment of HCC remain lacking.
Bo Xu +6 more
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Transplant InternationalLiving donor liver transplantation (LDLT) needs “Mercedes Benz” or “J-shaped” incision, causing short and long-term complications. An upper midline incision (UMI) is less invasive alternative but technically challenging.
Amit Rastogi +10 more
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PCSK9 promotes tumor growth by inhibiting tumor cell apoptosis in hepatocellular carcinoma
Experimental Hematology & Oncology, 2021 Background Proprotein convertase subtilisin/kexin type 9 (PCSK9), one of the key enzymes in the process of lipid transport, is involved in the disease progression of various types of tumors.
Shi-Zhe Zhang +6 more
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Bioengineering Liver Transplantation [PDF]
Bioengineering, 2019 Since the first in-man liver transplantation was performed by Starzl et al [...]
Monique M.A. Verstegen +2 more
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Signal Transduction and Targeted Therapy, 2022 Patients with hepatocellular carcinoma (HCC) have poor long-term survival following curative resection because of the high rate of tumor early recurrence. Little is known about the trajectory of genomic evolution from primary to early-recurrent HCC.
Shao-Lai Zhou +14 more
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