Results 31 to 40 of about 501,737 (303)

Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis

open access: yesCell Death and Disease, 2023
Multidrug resistance is a major challenge in treating advanced hepatocellular carcinoma (HCC). Although recent studies have reported that the multidrug resistance phenotype is associated with abnormal DNA methylation in cancer cells, the epigenetic ...
Xiao-Jun Guo   +17 more
doaj   +1 more source

Acute kidney injury and post-reperfusion syndrome in liver transplantation [PDF]

open access: yes, 2016
In the past decades liver transplantation (LT) has become the treatment of choice for patients with end stage liver disease (ESLD). The chronic shortage of cadaveric organs for transplantation led to the utilization of a greater number of marginal donors
Evison, Felicity   +8 more
core   +3 more sources

Amplification of spatially isolated adenosine pathway by tumor–macrophage interaction induces anti-PD1 resistance in hepatocellular carcinoma

open access: yesJournal of Hematology & Oncology, 2021
Background Immune checkpoint blockade resistance narrows the efficacy of cancer immunotherapies, but the underlying mechanism remains elusive. Delineating the inherent mechanisms of anti-PD1 resistance is important to improve outcome of patients with ...
Jia-Cheng Lu   +14 more
doaj   +1 more source

Liver transplantation for viral hepatitis in 2015 [PDF]

open access: yes, 2016
Liver transplantation (LT) is a life-saving treatment for patients with end-stage liver disease and for patients with liver cell cancer related to liver disease.
Bortoluzzi, Ilaria   +8 more
core   +1 more source

Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway

open access: yesCell Death Discovery, 2022
Hepatocellular carcinoma (HCC) is one of the most serious malignant cancers and has a high fatality rate. However, clinical strategies for the effective treatment of HCC remain lacking.
Bo Xu   +6 more
doaj   +1 more source

Indocyanine green elimination test in orthotopic liver recipients. [PDF]

open access: yes, 1996
OBJECTIVE: To determine its predictive capability on graft quality and resultant clinical outcome, the indocyanine green (ICG) elimination test was performed by a spectrophotometric method and a noninvasive finger-piece method with 50 orthotopic liver ...
Demetris, AJ   +6 more
core   +1 more source

Intestinal transplantation in children under FK 506 immunosuppression [PDF]

open access: yes, 1993
Intestinal transplantation, solitary (n = 3) or in combination with the liver (n = 7), was performed in 10 pediatric patients with intestinal failure. The liver was only replaced if there was liver failure and portal hypertension.
Adrian Casavilla   +26 more
core   +1 more source

Bioengineering Liver Transplantation [PDF]

open access: yesBioengineering, 2019
Since the first in-man liver transplantation was performed by Starzl et al [...]
Monique M.A. Verstegen   +2 more
openaire   +7 more sources

Minimizing Incision in Living Donor Liver Transplantation: Initial Experience and Comparative Analysis of Upper Midline Incision in 115 Recipients

open access: yesTransplant International
Living donor liver transplantation (LDLT) needs “Mercedes Benz” or “J-shaped” incision, causing short and long-term complications. An upper midline incision (UMI) is less invasive alternative but technically challenging.
Amit Rastogi   +10 more
doaj   +1 more source

PCSK9 promotes tumor growth by inhibiting tumor cell apoptosis in hepatocellular carcinoma

open access: yesExperimental Hematology & Oncology, 2021
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9), one of the key enzymes in the process of lipid transport, is involved in the disease progression of various types of tumors.
Shi-Zhe Zhang   +6 more
doaj   +1 more source

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