Results 21 to 30 of about 279,363 (257)

Serial circulating tumor DNA to predict early recurrence in patients with hepatocellular carcinoma: a prospective study

Molecular Oncology, 2022
We studied the value of circulating tumor DNA (ctDNA) in predicting early postoperative tumor recurrence and monitoring tumor burden in patients with hepatocellular carcinoma (HCC).
Gui‐Qi Zhu, Wei‐Ren Liu, Zheng Tang, Wei‐Feng Qu, Yuan Fang, Xi‐Fei Jiang, Shu‐Shu Song, Han Wang, Chen‐Yang Tao, Pei‐Yun Zhou, Run Huang, Jun Gao, Hai‐Xiang Sun, Zhen‐Bin Ding, Yuan‐Fei Peng, Zhi Dai, Jian Zhou, Jia Fan, Ying‐Hong Shi   +18 more
doaj   +1 more source

Successful use of the left portal vein as graft for middle hepatic vein reconstruction in left hemihepatectomy: preliminary experience on six cases

World Journal of Surgical Oncology, 2019
Background The purpose of this research was to assess the feasibility of reconstructing the middle hepatic vein (MHV) with resected left portal vein during left hemihepatectomy.
Tao Lv, Ling Xiang Kong, Jiayin Yang, Hong Wu, Tianfu Wen, Li Jiang, Jian Yang   +6 more
doaj   +1 more source

NCSTN promotes hepatocellular carcinoma cell growth and metastasis via β-catenin activation in a Notch1/AKT dependent manner

Journal of Experimental & Clinical Cancer Research, 2020
Background Hepatocellular carcinoma is the third top cause of cancer-related mortalities worldwide. The prognosis of HCC patients remains poor due to rapid progression and high incidence of tumor recurrence.
Hui Li, Tian Lan, Lin Xu, Hailing Liu, Jinju Wang, Jiaxin Li, Xiangzheng Chen, Jiwei Huang, Xuefeng Li, Kefei Yuan, Yong Zeng, Hong Wu   +11 more
doaj   +1 more source

De Novo Malignancies after Liver Transplantation: A Multicenter Cohort Study of Incidence, Timing, and Outcomes

The Turkish Journal of Gastroenterology
Background/Aims: De novo malignancies are an important long-term complication following liver transplantation (LT), driven by chronic immunosuppression and extended post-transplant survival.
Nilay Danış, Hüseyin Döngelli, Tarkan Ünek, Aylin Bacakoğlu, İlker Turan, Abdullah Zeki Karasu, Fulya Günşar, Elvan Işık, Muhsin Murat Harputluoglu, Kutay Sağlam, Sezai Yılmaz, Bilger Çavuş, Sabahattin Kaymakoglu, Haydar Adanır, Dinç Dinçer, Derya Arı, Meral Akdogan Kayhan, Dilara Turan Gokce, Gökhan Kabacam, Sedat Karademir, Murat Kıyıcı, Selcan Cesur, Hale Gokcan, Zeynep Melekoglu Ellik, Ramazan İdilman, Murat Dayangaç, Yasemin Balaban, Ahmet Bülent Doğrul, Hilmi Anıl Dinçer, Gupse Adalı, Feyza Dilber, Murat Taner Gulsen, Orhan Sezgin, Zekiye Nur Harput, Murat Akyıldız, Kenan Moral, Tufan Egeli, Cihan Ağalar, Mücahit Özbilgin, Mesut Akarsu   +39 more
doaj   +1 more source

Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis

Cell Death and Disease, 2023
Multidrug resistance is a major challenge in treating advanced hepatocellular carcinoma (HCC). Although recent studies have reported that the multidrug resistance phenotype is associated with abnormal DNA methylation in cancer cells, the epigenetic ...
Xiao-Jun Guo, Xiao-Yong Huang, Xuan Yang, Jia-Cheng Lu, Chuan-Yuan Wei, Chao Gao, Yan-Zi Pei, Yi Chen, Qi-Man Sun, Jia-Bin Cai, Jian Zhou, Jia Fan, Ai-Wu Ke, Yujiang G. Shi, Ying-Hao Shen, Peng-Fei Zhang, Guo-Ming Shi, Guo-Huan Yang   +17 more
doaj   +1 more source

Amplification of spatially isolated adenosine pathway by tumor–macrophage interaction induces anti-PD1 resistance in hepatocellular carcinoma

Journal of Hematology & Oncology, 2021
Background Immune checkpoint blockade resistance narrows the efficacy of cancer immunotherapies, but the underlying mechanism remains elusive. Delineating the inherent mechanisms of anti-PD1 resistance is important to improve outcome of patients with ...
Jia-Cheng Lu, Peng-Fei Zhang, Xiao-Yong Huang, Xiao-Jun Guo, Chao Gao, Hai-Ying Zeng, Yi-Min Zheng, Si-Wei Wang, Jia-Bin Cai, Qi-Man Sun, Ying-Hong Shi, Jian Zhou, Ai-Wu Ke, Guo-Ming Shi, Jia Fan   +14 more
doaj   +1 more source

Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway

Cell Death Discovery, 2022
Hepatocellular carcinoma (HCC) is one of the most serious malignant cancers and has a high fatality rate. However, clinical strategies for the effective treatment of HCC remain lacking.
Bo Xu, Yonggang Wei, Fei Liu, Lian Li, Siqi Zhou, Yufu Peng, Bo Li   +6 more
doaj   +1 more source

Minimizing Incision in Living Donor Liver Transplantation: Initial Experience and Comparative Analysis of Upper Midline Incision in 115 Recipients

Transplant International
Living donor liver transplantation (LDLT) needs “Mercedes Benz” or “J-shaped” incision, causing short and long-term complications. An upper midline incision (UMI) is less invasive alternative but technically challenging.
Amit Rastogi, Ankur A. Gupta, Raghav Bansal, Fysal Kollanta Valappil, Kamal S. Yadav, Suchet Chaudhary, Prashant Bhangui, Swapnil Dhampalvar, Narendra S. Choudhary, Neeraj Saraf, Arvinder S. Soin   +10 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Hepatic Duct Division During Robotic Living Donor Hepatectomy: A Comparison Between the Novel Triple C (Clip–Clamp–Cut) and the Cut–Suture Techniques

Journal of Transplantation
Conclusions: Our simple yet novel triple C technique enables clean, precise, bloodless HDD resulting in lower donor and potentially recipient biliary complication rates. The ease and reproducibility make it ideal for widespread adoption.
Arvinder S. Soin, Kamal S. Yadav, Fysal Valappil, Nikhitha Shetty, Raghav Bansal, Suchet Chaudhary, Ankur Gupta, Amit Rastogi, Prashant Bhangui   +8 more
doaj   +1 more source