Results 41 to 50 of about 427,437 (355)

Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis

Cell Death and Disease, 2023
Multidrug resistance is a major challenge in treating advanced hepatocellular carcinoma (HCC). Although recent studies have reported that the multidrug resistance phenotype is associated with abnormal DNA methylation in cancer cells, the epigenetic ...
Xiao-Jun Guo, Xiao-Yong Huang, Xuan Yang, Jia-Cheng Lu, Chuan-Yuan Wei, Chao Gao, Yan-Zi Pei, Yi Chen, Qi-Man Sun, Jia-Bin Cai, Jian Zhou, Jia Fan, Ai-Wu Ke, Yujiang G. Shi, Ying-Hao Shen, Peng-Fei Zhang, Guo-Ming Shi, Guo-Huan Yang   +17 more
doaj   +1 more source

Psychiatric and psychosocial outcome of orthotopic liver transplantation [PDF]

, 2002
Background. The study aimed to explore the prevalence of psychiatric disorders among orthotopic liver transplantation (OLT) recipients, and to investigate how psychiatric morbidity was linked to health-related quality of life (HRQOL).
Rothenhäusler, Hans-Bernd, Kapfhammer, Hans-Peter, Ehrentraut, Sigrid, Bilzer, Manfred, Schelling, Gustav, Lang, Christina, Gerbes, Alexander L., Zachoval, Reinhart   +7 more
core   +1 more source

Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway

Cell Death Discovery, 2022
Hepatocellular carcinoma (HCC) is one of the most serious malignant cancers and has a high fatality rate. However, clinical strategies for the effective treatment of HCC remain lacking.
Bo Xu, Yonggang Wei, Fei Liu, Lian Li, Siqi Zhou, Yufu Peng, Bo Li   +6 more
doaj   +1 more source

Osteoporosis in Pediatric Liver Transplantation [PDF]

, 2016
Liver transplantation provides an important, often life-saving treatment for end-stage liver disease. Osteoporosis post-liver transplantation has been described in adults; however, this has not been described in the pediatric population to date.
El Nounou, Ghina, Al Naaj, Abdallah Abou, Haydar, Ali A., Nancy Nakhoul, Mohammad Khalife, Walid Faraj, Ali Haydar, Khalife, Mohamad Jawad, Ghina El Nounou, Abdallah Abou Al Naaj, Nakhoul, Nancy F., Faraj, Walid G.   +11 more
core   +1 more source

GSH Attenuates Organ Injury and Improves Function after Transplantation of Fatty Livers [PDF]

, 2010
Ischemia-reperfusion injury (IRI) is increased after transplantation of steatotic livers. Since those livers are increasingly used for transplantation, protective strategies must be developed. Reactive oxygen species (ROS) play a key role in hepatic IRI.
Jauch, Karl-Walter, S. Pratschke, U. Grützner, Gruetzner, U., Angele, M. K., F. Loehe, M. Bilzer, M.K. Angele, Tufman, A., Löhe, F., Schauer, R. J., Bilzer, M., Pratschke, S., A. Tufman, K.-W. Jauch, R.J. Schauer   +15 more
core   +1 more source

PCSK9 promotes tumor growth by inhibiting tumor cell apoptosis in hepatocellular carcinoma

Experimental Hematology & Oncology, 2021
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9), one of the key enzymes in the process of lipid transport, is involved in the disease progression of various types of tumors.
Shi-Zhe Zhang, Xiao-Dong Zhu, Long-Hai Feng, Xiao-Long Li, Xue-Feng Liu, Hui-Chuan Sun, Zhao-You Tang   +6 more
doaj   +1 more source

Survival after liver transplantation in the United Kingdom and Ireland compared with the United States

, 2007
<b>Background and Aim</b>: Surgical mortality in the US is widely perceived to be superior to that in the UK. However, previous comparisons of surgical outcome in the two countries have often failed to take sufficient account of case-mix or ...
van der Meulen, JHP, Copley, LP, van der Meulen, J., Gimson, AE, Lewsey, J.D., Dawwas, M.F., Gimson, A.E., Lewsey, JD, Copley, L.P., Dawwas, MF   +9 more
core   +1 more source

Multimodality Treatment for Early-Stage Hepatocellular Carcinoma: A Bridging Therapy for Liver Transplantation [PDF]

, 2012
Purpose: To evaluate the efficiency of a multimodality approach consisting of transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) as bridging therapy for patients with hepatocellular carcinoma (HCC) awaiting orthotopic liver
Rentsch, M., P. Paprottka, F.T. Kolligs, Siegert, S., Kolligs, F. T., R.T. Hoffmann, Hoffmann, Ralf-Thorsten, Reiser, Maximilian F., Paprottka, Philipp M., D’Anastasi, Melvin, Jakobs, Tobias F., N. Ashoori, J.A. Al-Tubaikh, M.F. Reiser, Ashoori, Nima, M. Rentsch, Al-Tubaikh, J. A., Paprottka, P., Al-Tubaikh, Jarrah Ali, T.F. Jakobs, Kolligs, Frank T., Rentsch, Markus, Peporte, A., Hoffmann, R. T., M. D’Anastasi, Jakobs, T. F., D'Anastasi, M., Ashoori, N., Siegert, Sabine, S. Siegert, Bamberg, Fabian, F. Bamberg, Bamberg, F., A. Peporte   +33 more
core   +1 more source

Minimizing Incision in Living Donor Liver Transplantation: Initial Experience and Comparative Analysis of Upper Midline Incision in 115 Recipients

Transplant International
Living donor liver transplantation (LDLT) needs “Mercedes Benz” or “J-shaped” incision, causing short and long-term complications. An upper midline incision (UMI) is less invasive alternative but technically challenging.
Amit Rastogi, Ankur A. Gupta, Raghav Bansal, Fysal Kollanta Valappil, Kamal S. Yadav, Suchet Chaudhary, Prashant Bhangui, Swapnil Dhampalvar, Narendra S. Choudhary, Neeraj Saraf, Arvinder S. Soin   +10 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source