Results 171 to 180 of about 520,167 (196)

Liver X Receptors

Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents, 2002
Xiao Hu, Deepak Lala
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Limonoids as liver X receptor modulators

2022
Atherosklerotische Herz-Kreislauf-Erkrankungen verursachen klinische Endpunkte wie den Myokardinfarkt und Schlaganfall und stellen somit die häufigste Todesursache weltweit dar. Der Liver X Rezeptor (LXR) übernimmt eine Vielzahl an regulatorischen Aufgaben im Cholesterinmetabolismus und eignet sich deshalb als ein ausgezeichnetes Target in der ...
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Liver X receptors and atherosclerosis.

IDrugs : the investigational drugs journal, 2004
Cardiovascular disease, the primary cause of death and illness in the industrialized world, is typically due to complications of atherosclerosis, a multifactorial disease of the arterial intima. The liver X receptors (LXRs), LXRalpha and LXRbeta, are intracellular receptors that appear to play an important role in protection against atherosclerosis ...
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Liver X Receptors in Bacterial Clearance

Science's STKE, 2004
Liver X receptors (LXRs) are well known for acting as heterodimers with retinoid X receptors (RXRs) to regulate the expression of genes involved in lipid metabolism. Joseph et al . expand the role of the LXRα isoform to include regulation of susceptibility to bacterial infection.
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[Recent advances on liver X receptors].

Sheng li ke xue jin zhan [Progress in physiology], 2012
The liver X receptors (LXRs), that are nuclear receptors activated by oxysterols, play central roles in the transcriptional control of cholesterol metabolism and function as the sensors of cholesterol homeostasis. In addition, LXRs have also been found to modulate lipogenesis, carbohydrate metabolism, innate immune and inflammatory responses in ...
Qiang, Wang, Yu, Jiang
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The gut–liver axis and gut microbiota in health and liver disease

Nature Reviews Microbiology, 2023
Cynthia Li-Shin Hsu, Bernd Schnabl
exaly  

Advances in the treatment of intrahepatic cholangiocarcinoma: An overview of the current and future therapeutic landscape for clinicians

Ca-A Cancer Journal for Clinicians, 2023
Demetrios Moris
exaly  

Liver regeneration and inflammation: from fundamental science to clinical applications

Nature Reviews Molecular Cell Biology, 2021
Lara Campana, Meritxell Huch, Stuart Forbes   +2 more
exaly  

Biological role of liver X receptors.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009
Liver X receptors (LXRs) are ligand-activated transcription factors of the nuclear receptor superfamily. There are two LXR isoforms termed alpha and beta which upon activation form heterodimers with retinoid X receptor and bind to LXR response element found in the promoter region of the target genes.
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Disparities in liver cancer occurrence in the United States by race/ethnicity and state

Ca-A Cancer Journal for Clinicians, 2017
Farhad Islami, Rebecca L Siegel, Elizabeth M Ward   +2 more
exaly