Results 121 to 130 of about 3,379,585 (304)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Editorial: A Living History of Immunology. [PDF]
Front Immunol, 2015 Smith KA.
europepmc +1 more source
, 2016 Salona je izrazito vrijedan i značajan arheološki lokalitet, čiji je današnji glavni ulaz smješten u rubnoj zoni zaštićenog arheološkog parka te je neadekvatno uređen i slabo kontroliran. Projekt se bavi uređenjem prostora kroz izgradnju multifunkcionalnog kompleksa kojem je glavni sadržaj hotel visoke kategorije, a osnovna zadaća prezentacija baštine ...
openaire +1 more source
Micro-Perspectives on Living Standards in Nineteenth-Century Russia [PDF]
In recent years economic historians have turned new attention to questions about standards of living in pre-revolutionary Russia. However, most of the studies to date have focused on a narrow range of measures for predominantly urban areas.
Steven Nafziger, Tracy Dennison
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Homelessness in New Zealand [PDF]
Introduction: This paper examines homelessness in New Zealand, particularly those people living without shelter and in temporary accommodation given they can experience severe health problems.
Paul Bellamy
core
[Review of] Jay C. Chunn, II, Patricia J. Dunston, and Fariyal Ross-Sheriff, eds. Mental Health and People of Color: Curriculum Development and Change [PDF]
, 1984 American colleges, universities, and medical schools have developed elaborate structures for the study, diagnosis, treatment, and prevention of mental illness and associated problems in living. The history of psychological training is not value free, but
Abbott, Linda M. C.
core +1 more source