Results 121 to 130 of about 3,377,831 (304)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

To Be or Not to Be: Thoughts on Living History - Some Personal Remarks

open access: yesEXARC Journal, 2012
This article is based on personal experiences and observations conducted through many years as a volunteer at the Middle Age Centre in Denmark and later as a student at the Open Air Museum, Sorgenfri, Denmark.
Thit Birk Petersen
doaj  

Homelessness in New Zealand [PDF]

open access: yes
Introduction: This paper examines homelessness in New Zealand, particularly those people living without shelter and in temporary accommodation given they can experience severe health problems.
Paul Bellamy
core  

From Extrinsic Design to Intrinsic Teleology [PDF]

open access: yes, 2019
In this paper I offer a distinction between design and teleology, referring mostly to thehistory of these two terms, in order to suggest an alternative strategy for arguments thatintend to demonstrate the existence of the divine.
Silva, Ignacio
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

EXARC at the Times and Epochs Festival, Kolomenskoye Park, Moscow

open access: yesEXARC Journal, 2013
As an EXARC Board member, I attended the Times and Epochs Festival in Moscow from June 21-23, 2013 in the open-air museum Kolomenskoye Park. This year, an estimated 200,000 people attended the medieval themed festival where they were able to witness and ...
Bill Schindler
doaj  

Glyptostrobus europaeus (Brongn.) Heer in Arkansas [PDF]

open access: yes, 1970
Glyptostrobus europaeus (Brongn.) Heer, a fossil gymnosperm is found at a few locations in central North America, in deposits of the Eocene. This work cites previously reported localities and reports a new site at Hooker, Arkansas.
Wittlake, Eugene B.
core   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

I Know What you Did Last Summer

open access: yesEXARC Journal, 2013
It was during a field trip to the National Archives with a group of college students that I first became aware of the problem. We had traveled to Washington D.C. to view the exhibit titled, What’s Cooking, Uncle Sam?
Bill Schindler
doaj  

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