Results 151 to 160 of about 3,379,585 (304)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Crafting the Past: Theory and Practice of Museums
EXARC Journal, 2013 How do we know something is real? We say something exists when it is tangible and we can touch it; it is factual when we can compare it to other known variables, and historic when it fulfils our expectation of the past.
Katherine Ambry Linhein Muller
doaj
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Physical stature and its interpretation in nineteenth century New Zealand [PDF]
During the late nineteenth century the physical stature of New Zealandborn men stagnated, despite an apparently beneficial public health environment and growth in per-capita incomes.
Evan Roberts, Kris Inwood, Les Oxley
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Where Two Worlds Meet - Living History and Heritage Locations
EXARC JournalThe Netherlands have an abundance of heritage locations: museums, monuments, windmills. A favorite pastime of many senior citizens is to take responsibility for this heritage as volunteer guides, amateur historians, and so on.
Luc Eekhout
doaj
[Book Review of] Easterly, William: The elusive quest for growth : economists' adventures and misadventures in the tropics : Cambridge, MA : MIT Press, 2001. [PDF]
Easterly has written a unique book about the international differences in the standard of living, which have never been larger in the history of mankind than today.
Gundlach, Erich
core
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source