Results 181 to 190 of about 912,341 (301)

Living Lab for Citizens' Wellness: A Case of Maintaining and Improving a Healthy Diet under the COVID-19 Pandemic. [PDF]

Int J Environ Res Public Health, 2022
Tabata N, Tsukada M, Kubo K, Inoue Y, Miroku R, Odashima F, Shiratori K, Sekiya T, Sengoku S, Shiroyama H, Kimura H.   +10 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Living Lab Dementia: Mixed-methods process evaluation of a feasibility study of an academic-practice partnership in German long-term dementia care. [PDF]

BMC Geriatr
Bühler F, Leinen A, Bieber A, Köpke S, Meyer G, Seismann-Petersen S, Dichter MN.   +6 more
europepmc   +1 more source

Complex urban systems: a living lab to understand urban processes and solve complex urban problems. [PDF]

Eur Phys J Spec Top, 2022
Becker KH, Bello JP, Porfiri M.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Design Ideas for Inpatient Stroke Rehabilitation Facilities: Living Lab Findings. [PDF]

HERD
Lipson-Smith R, Davis A, White M, Pflaumer L, Davey J, Churilov L, Fox A, Pitt N, Shiggins C, Saa JP, Lam M, Bernhardt J, NOVELL Collaboration.   +12 more
europepmc   +1 more source

Co-creating Virtual Reality Interventions for Alcohol Prevention: Living Lab vs. Co-design. [PDF]

Front Public Health, 2021
Dietrich T, Guldager JD, Lyk P, Vallentin-Holbech L, Rundle-Thiele S, Majgaard G, Stock C.   +6 more
europepmc   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Navigating Canada's primary care crisis: Living Lab approach to reduce administrative burden. [PDF]

Can Fam Physician
Gilfoyle M, Pearce S, Ha E, Kthupi A, Miceli L, Tibbles A, Agarwal P, Bhattacharyya O.   +7 more
europepmc   +1 more source