Results 121 to 130 of about 237,580 (299)

Urban Living Labs: how to enable inclusive transdisciplinary research? [PDF]

Urban Transform, 2021
Laborgne P, Ekille E, Wendel J, Pierce A, Heyder M, Suchomska J, Nichersu I, Balaican D, Ślebioda K, Wróblewski M, Goszczynski W.   +10 more
europepmc   +1 more source

A Living Lab as a Service: Creating Value for Micro-enterprises through Collaboration and Innovation [PDF]

, 2013
The need to innovate is increasingly important for all types and sizes of organizations, but the opportunities for innovation differ substantially between them.
Anna Ståhlbröst
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Actor Roles in an Urban Living Lab: What Can We Learn from Suurpelto, Finland? [PDF]

Technology Innovation Management Review, 2013
There is a growing trend to involve citizens in city development to make urban areas more suitable to their needs and prevent social problems. City centres and neighbourhoods have increasingly been serving as regional living labs, which are ideal ...
Soile Juujärvi, Kaija Pesso
doaj  

A co-design living labs philosophy of practice for end-to-end research design to translation with people with lived-experience of mental ill-health and carer/family and kinship groups. [PDF]

Front Public Health, 2023
Palmer VJ, Bibb J, Lewis M, Densley K, Kritharidis R, Dettmann E, Sheehan P, Daniell A, Harding B, Schipp T, Dost N, McDonald G.   +11 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Living labs as orchestrators in the regional innovation ecosystem: a conceptual framework

Journal of Responsible Innovation
This research explores the conceptual integration of Living Labs (LLs) into the Regional Innovation Ecosystem (RIE) to understand their potential as facilitators of Responsible Innovation.
Janin Fauth, Kevin De Moortel, Dimitri Schuurman   +2 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A Secure Data Publishing and Access Service for Sensitive Data from Living Labs: Enabling Collaboration with External Researchers via Shareable Data

Big Data and Cognitive Computing
Intending to enable a broader collaboration with the scientific community while maintaining privacy of the data stored and generated in Living Labs, this paper presents the Shareable Data Publishing and Access Service for Living Labs, implemented within ...
Mikel Hernandez, Evdokimos Konstantinidis, Gorka Epelde, Francisco Londoño, Despoina Petsani, Michalis Timoleon, Vasiliki Fiska, Lampros Mpaltadoros, Christoniki Maga-Nteve, Ilias Machairas, Panagiotis D. Bamidis   +10 more
doaj   +1 more source

Protocol for a systematic review of living labs in healthcare. [PDF]

BMJ Open, 2021
Archibald M, Wiebe S, Rieger K, Linton J, Woodgate R.   +4 more
europepmc   +1 more source