Results 61 to 70 of about 237,580 (299)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Living labs as a driver for change in regional television [PDF]

open access: yes, 2014
Traditional television production and distribution organizations are increasingly being challenged by a rapidly changing technological environment. These evolutions force the television industry to leave their comfort zone. This context in mind, regional
Baccarne, Bastiaan, Schuurman, Dimitri
core  

Barrierefreier Tourismusraum Bodensee [PDF]

open access: yes, 2017
Das Projekt "Barrierefreier Tourismusraum Bodensee" ist ein Projekt des IBH Living Labs AAL1, das von der Internationalen Bodensee Hochschule IBH gefördert wird und bei dem Hochschul- und Praxispartner aus der Schweiz, Deutschland und Österreich ...
Darvishy, Alireza, Hutter, Hans-Peter
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Mapping Living Labs in the Landscape of Innovation Methodologies [PDF]

open access: yesTechnology Innovation Management Review, 2012
A growing interest in living labs as a mechanism for innovation has drawn significant attention to both the different flavours of this methodology and to the organizations that put it into practice.
Melissa Lee   +2 more
doaj  

Marco metodológico para la implementación y evaluación de Living Labs [PDF]

open access: yes, 2008
El Living Lab constituye un enfoque de investigación para la innovación que desafía todo el proceso de innovación e investigación en condiciones de la vida real mediante aspectos institucional, organizacional, cultural, social y humano, teniendo un ...
García Guzmán, Javier
core   +1 more source

Report on the CIKM workshop on living labs for information retrieval evaluation [PDF]

open access: yes, 2014
Evaluation is a central aspect of information retrieval (IR) research. In the past few years, a new evaluation methodology known as living labs has been proposed as a way for researchers to be able to perform in-situ evaluation.
Balog, Krisztian   +4 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The Defining Characteristics of Urban Living Labs

open access: yesTechnology Innovation Management Review, 2017
The organization of supported and sustainable urban interventions is challenging, with multiple actors involved, fragmented decision-making powers, and multiple values at stake.
Kris Steen, Ellen van Bueren
doaj  

How can campus living labs thrive to reach sustainable solutions?

open access: yesCleaner Production Letters
Many Higher Education Institutions utilize living labs to address complex societal challenges and foster innovative and sustainable solutions on campus.
Annika Herth   +2 more
doaj   +1 more source

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