Results 91 to 100 of about 284,893 (258)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Research on resilience regulation of water resource systems in the Yellow River basin under during extreme drought years

open access: yesShui kexue jinzhan
Under changing environmental conditions,water-scarce basins are facing increasingly severe conflicts between water supply and demand. Therefore,there is an urgent need to innovate and develop methods and technologies to regulate water resource resilience
Yu WANG   +6 more
doaj   +1 more source

Electric and magnetic phenomena in water and living systems [PDF]

open access: yes
We are called organisms because our cells are organized into a cooperative\ud assemblage of interacting elements. Human beings are more\ud than simply bags of interacting chemicals walking around enclosed\ud within 1.8 square metres of skin. It has long been known that\ud biological organisms, including ourselves, use chemical communication\ud systems.
openaire  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

From Prototypes to Living Labs: Advancing Sustainability Education in Rwanda and Côte d’Ivoire

open access: yesJournal of Sustainable Development of Energy, Water and Environment Systems
This paper evaluates the outcomes of two projects, “Industry-Integrated Dual Engineering Studies in a North-South Collaboration" in Côte d’Ivoire and "Growing Rwanda Energy Awareness Through Higher Education" in Rwanda.
Lisa Schmitt   +2 more
doaj   +1 more source

A Systematic Literature Review on Flow Data-Based Techniques for Automated Leak Management in Water Distribution Systems

open access: yesSmart Cities
Smart cities integrate advanced technologies, data-driven decision-making, and interconnected infrastructure to enhance urban living and resource efficiency.
Gopika Rajan, Songnian Li
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Dynamic entity formed by protein and its hydration water

open access: yesPhysical Review Research
The interaction between protein and water plays a pivotal role in shaping the structure, dynamics, and function of biomacromolecules. A comprehensive understanding of this intricate interplay necessitates a systematic evaluation of interaction strength ...
Yongfeng Ye   +15 more
doaj   +1 more source

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