Results 161 to 170 of about 57,467,955 (246)

Chronic Disease and Disability in the United States: Trends, Inequities, and Imperatives for Policy Reform

The Milbank Quarterly, EarlyView.
Policy Points Position Universal, High‐Quality Education as a Foundational Public Health Strategy. Long‐term health and life expectancy in the United States are shaped more by educational attainment than by any other single factor. Disparities in access to early childhood, K‐12, and higher education perpetuate cycles of chronic disease, economic ...
ALI H. MOKDAD, LAURA DWYER‐LINDGREN, CHRISTOPHER J.L. MURRAY   +2 more
wiley   +1 more source

OT-CATH, a conserved antimicrobial peptide in <i>Otariidae</i> species, exhibits potent activity against gram-negative bacteria. [PDF]

Antimicrob Agents Chemother
Song Y, Ren Y, Wang J, Ye Z, Shi C, Kong X, Jiao X, Zhang J, Wang Y.   +8 more
europepmc   +1 more source

Inhibin βB Mediates Oligotrophic Adaptation via Regulating Muscle Satellite Cell Proliferation and Differentiation in Schizopygopsis younghusbandi

Integrative Zoology, EarlyView.
① Nutrient deficiency upregulates inhibin βB, activating SMAD signaling to promote p21. Increased p21 inhibits mcm2/mcm4/mcm5 and cyclin E2, inducing G1‐phase arrest, slowing growth, and reducing energy consumption. ② Inhibin βB also upregulates pdgf‐c, which induces α‐SMA, leading to muscle satellite cell fibrosis.
Weiqiang Li, He Gao, Chaowei Zhou, Luo Lei, Junting Li, Chao Ma, Zitu Ma, Mengwei Yao, Kexin Ma, Yunpeng Xiang, Yan Zhou, Yongrui Lu, Da Ji, Minghong Wei, Luohao Xu, Zhaofang Han, Haiping Liu   +16 more
wiley   +1 more source

Post-translational modifications in rosacea. [PDF]

Front Immunol
Zhang X, Su H, Deng W, Liu F, Liu S.
europepmc   +1 more source

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source

Association of Vitamin D Supplementation with VDR and CAMP Expression and Ulcer Healing in Diabetic Foot Infection Involving Biofilm-Forming Bacteria: An Exploratory Prospective Cohort Study. [PDF]

Pharmaceuticals (Basel)
Benson R, Velladath SU, Prasad SS, Nittur S, Banerjee B, Rodrigues GS, Rao M, Hariharapura RC, Munisamy M, Vishwanath S, Mukhopadhyay C, Sudha Gururaj VK, Miraj SS.   +12 more
europepmc   +1 more source

Autoimmune neutropenia in children: Test cells versus beads and a role for pro‐LL‐37 and absolute neutrophil count

British Journal of Haematology, EarlyView.
A comparison between bead‐based and cell‐based assays for autoantibody detection in childhood neutropenia revealed substantial discordance between platforms. Bead‐based methods should be complemented with cell‐based methods for optimal diagnostic sensitivity. Incorporating pro‐LL‐37 and ANC measurements into the clinical workup of childhood neutropenia
Paul Ratcliffe, Alexandra Haara Löfstedt, Mikael Sundin, Petter Höglund   +3 more
wiley   +1 more source

Correction to "Self-assembly of PEG-PPS polymers and LL-37 peptide nanomicelles improves the oxidative microenvironment and promotes angiogenesis to facilitate chronic wound healing". [PDF]

Bioeng Transl Med
europepmc   +1 more source

Antimicrobial Peptides for Diabetic Foot Ulcers and Infections: Current Evidence and Translational Perspectives. [PDF]

Int J Mol Sci
Khotina VA, Lee AA, Kashirskikh DA, Klychkova OO, Novikova VS, Markina MP, Voronko OE, Gasanov VAO.   +7 more
europepmc   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source