Results 1 to 10 of about 17,552 (216)

Cathelicidin Contributes to the Restriction of Leishmania in Human Host Macrophages

open access: yesFrontiers in Immunology, 2019
In cutaneous Leishmaniasis the parasitic control in human host macrophages is still poorly understood. We found an increased expression of the human cathelicidin CAMP in skin lesions of Ethiopian patients with cutaneous leishmaniasis.
Ger van Zandbergen   +2 more
exaly   +4 more sources

Cathelicidin-OA1, a Novel Antioxidant Peptide Identified From an Amphibian, Accelerates Skin Wound Healing

open access: yesScientific Reports, 2018
Cathelicidins play pivotal roles in host defense. The discovery of novel cathelicidins is important research; however, despite the identification of many cathelicidins in vertebrates, few have been reported in amphibians.
Chunyun Wu, Xinwang Yang, Zhe Fu
exaly   +3 more sources

The antimicrobial peptide cathelicidin protects mice from Escherichia coli O157:H7-mediated disease. [PDF]

open access: yesPLoS ONE, 2012
This study investigated the role of the antimicrobial peptide cathelicidin in Escherichia coli O157:H7 infection and subsequent renal damage. Mouse and human cathelicidin, CRAMP and LL-37, respectively, killed E. coli O157:H7 in vitro.
Milan Chromek   +2 more
doaj   +3 more sources

Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics. [PDF]

open access: yesPLoS ONE, 2008
BACKGROUND: Cathelicidins are a family of antimicrobial peptides acting as multifunctional effector molecules of innate immunity, which are firstly found in mammalians. Recently, several cathelicidins have also been found from chickens and fishes.
Yipeng Wang   +8 more
doaj   +3 more sources

Cathelicidin-Mediated Lipopolysaccharide Signaling via Intracellular TLR4 in Colonic Epithelial Cells Evokes CXCL8 Production

open access: yesGut Microbes, 2020
We hypothesized that the antimicrobial peptide cathelicidin has a physiological role in regulating gut inflammatory homeostasis. We determined that cathelicidin synergizes with LPS to facilitate its internalization and signaling via endosomic TLR4 in ...
Eduardo Cobo   +2 more
exaly   +2 more sources

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation [PDF]

open access: yesExperimental Physiology
Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS ...
Mehrdad Nourizadeh   +6 more
doaj   +2 more sources

Association of serum cathelicidin and Vitamin D levels with infectiousness in patients with pulmonary tuberculosis: A prospective cohort study

open access: yesInternational Journal of Mycobacteriology, 2023
Background: The immunomodulatory effects of Vitamin D expand to induce the synthesis of an antimicrobial peptide, cathelicidin. There is evidence showing altered levels of cathelicidin in tuberculosis (TB).
Yuvaraj Balan   +4 more
doaj   +1 more source

Immunomodulatory effects of chicken cathelicidin-2 on a primary hepatic cell co-culture model

open access: yesPLoS ONE, 2022
Cathelicidin-2 is an antimicrobial peptide (AMP) produced as part of the innate immune system of chickens and might be a new candidate to combat infection and inflammation within the gut-liver axis.
Csilla Sebők   +9 more
doaj   +2 more sources

Cathelicidin, vitamin D3 dan imunitas terhadap tuberkulosis

open access: yesJKS (Jurnal Kedokteran Syiah Kuala), 2020
Abstrak. Tuberkulosis (TB) merupakan salah satu penyakit infeksi yang menjadi masalah di dunia. Risiko untuk mendapatkan infeksi TB dipengaruhi oleh imunitas alamiah melawan mikobakteria.
Yunita Arliny, Maryatun Hasan
doaj   +1 more source

Circulating Cathelicidin Concentrations in a Cohort of Healthy Children: Influence of Age, Body Composition, Gender and Vitamin D Status. [PDF]

open access: yesPLoS ONE, 2016
Cathelicidin is an antimicrobial peptide whose circulating levels are related to vitamin D status in adults. This study sought to determine if circulating cathelicidin concentrations in healthy children are related to the age of the child, body ...
Taylor M Stukes   +8 more
doaj   +1 more source

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