Results 201 to 210 of about 57,467,955 (246)

Emerging locally delivered antimicrobial and immunomodulatory approaches for the prevention/treatment of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje, Ettore Amerio, Irene Mallor, Conrado Aparicio   +3 more
wiley   +1 more source

Impact of 14 days of head‐down bed rest and an exercise countermeasure on skeletal muscle atrophy, proteome and circulatory cytokines in older adults

Experimental Physiology, EarlyView.
Abstract Prolonged bed rest and immobilization have deleterious effects on skeletal muscle mass and function, especially in older adults. These can lead to reduced physical capacity and quality of life. Previous experiments in younger individuals show that exercise can mitigate these effects, but evidence remains scarce and inconclusive in older adults.
Jean‐Christophe Lagacé, Philippe St‐Martin, Mariano Avino, Ahmed Ghachem, Guy Hajj‐Boutros, Jose A. Morais, Jamie S. McPhee, Karen Lambert, Eléonor Riesco, Isabelle J. Dionne   +9 more
wiley   +1 more source

Exploratory Evaluation of Susceptibility Patterns of Clinical Isolates of <i>Acinetobacter baumannii</i> Towards Polymyxins and Different Cationic Antimicrobials. [PDF]

Antibiotics (Basel)
Shahzad S, Willcox MDP, Jamil B, Rayamajhee B, Yasir M.   +4 more
europepmc   +1 more source

TRIP8bnano peptide prevents cAMP binding to HCN2 channels alleviating pain‐like behaviors in rats with neuropathic pain

The Journal of Physiology, EarlyView.
Abstract figure legend We tested the hypothesis that cAMP binding to HCN2 channels in nociceptors is a causal driver of neuropathic pain by using TRIP8bnano, a synthetic peptide we previously developed as a selective antagonist of cAMP in HCN channels. TRIP8bnano effectively abolishes cAMP potentiation of HCN2 currents in small‐diameter DRG neurons and
Santiago I. Loya‐Lopez, Kimberly Gomez, Alessandro Porro, Gerhard Thiel, Anna Moroni, Heather N. Allen, Rajesh Khanna, Andrea Saponaro   +7 more
wiley   +1 more source

LL-37 inhibits osteosarcoma progression by suppressing SQLE-mediated cholesterol synthesis via the PTEN/AKT/mTOR pathway. [PDF]

J Bone Oncol
Lu F, Liu Z, Jiang H, Zheng H, Su W, Zhou B.   +5 more
europepmc   +1 more source

Surface Ligand Engineering in Quantum Dot Photocatalysis: Mechanisms, Design Principles, and Applications

Advanced Chemical Engineering, Volume 1, Issue 2, December 2026.
Surface ligands govern quantum dot photocatalysis through thermodynamic band‐edge tuning, kinetic charge‐transfer regulation, and microenvironmental control. Rational ligand engineering, using short‐chain, inorganic, conjugated, or dual‐ligand systems, enables efficient solar fuel production, selective organic transformations, environmental remediation,
Yali Weng, Huakang Yang, Zining Zhang, Yue Zhou, Dongxiang Luo, Xiao Liu   +5 more
wiley   +1 more source

Reframing Antimicrobial Peptides beyond Direct Antimicrobial Activity toward Host-Directed Functions and Disease-Specific Therapeutic Applications. [PDF]

J Microbiol Biotechnol
Lee M.
europepmc   +1 more source

Teleport‐stabilised quantum‐walk transport for robust neoantigen ranking in near‐tie regimes: A reproducible colorectal benchmark

Clinical and Translational Discovery, Volume 6, Issue 6, December 2026.
Teleport‐stabilised quantum‐walk transport for robust neoantigen ranking in near‐tie regimes. The analysis proceeds from patient‐conditioned candidate definition to weighted evidence‐graph construction, quotient‐basin compression, continuous‐time quantum‐walk (CTQW)/discrete‐time quantum walk (DTQW) transport, teleport‐consensus stabilisation, ABHA ...
Ioannis Grigoriadis
wiley   +1 more source

Antimicrobial peptoids pass rapidly through bacterial membranes and flocculate ribosomes and DNA: A single-cell fluorescence study. [PDF]

Proc Natl Acad Sci U S A
Zhu Y, Nielsen JE, Molchanova N, Mustafi M, Herlan C, Fleck B, Bräse S, Schepers U, Sørensen K, Zielke C, Lin JS, Weisshaar JC, Jenssen H, Barron AE.   +13 more
europepmc   +1 more source

Foamed Concrete Sealing Materials for Coal Seam Gas Drainage Boreholes: A Review

Safety Science and Technology, Volume 1, Issue 4, December 2026.
This study investigates the sealing performance of foamed concrete in gas drainage boreholes. By comparing leakage pathways (a, c) with sealed systems (b, d), the research demonstrates how foamed concrete effectively fills mining‐induced fractures and resists deformation.
Jiaxing Zou, Erlei Su, Huanchun Liu, Xiangjun Chen, Lin Wang, Haidong Chen, Lin Li   +6 more
wiley   +1 more source