Results 61 to 70 of about 1,395,480 (391)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

City Wide Adhan as heard from near Masgid Sheikh Abdullah on 02-07-2010 at 5:36pm: Maghrib Adhan [PDF]

open access: yes, 2010
Five times a day in the 83 square mile city of Cairo, over 30,000 muezzins call out the adhan, or call to prayer, calling believers to come and to pray.
Kipervaser, Anna, LLC, On Look Films
core  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Caracterização mecânica e estrutural de um dispositivo PDLC baseado em hidrogéis de PAAm e cristal líquido liotrópico LP/DeOH/H2O

open access: yesQuímica Nova, 2014
In this work, a novel device based on polyacrylamide (PAAm) hydrogels and KL - DeOH - H2O lyotropic liquid crystal (LLC), with potential for application as Polymer Dispersed Liquid Crystals (PDLC), was proposed and its properties characterized.
Fauze A. Aouada   +4 more
doaj   +1 more source

Ameliorating cancer cachexia by inhibiting cancer cell release of Hsp70 and Hsp90 with omeprazole

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2022
Background Cancer cachexia, characterized by muscle and fat tissue wasting, is a major determinant of cancer‐related mortality without established treatment. Recent animal data revealed that cancer cells induce muscle wasting by releasing Hsp70 and Hsp90
Zhelong Liu   +7 more
doaj   +1 more source

City Wide Adhan as heard from near Masgid Sheikh Abdullah on 08-20-2010 at 7:54pm: ‘Isha Adhan [PDF]

open access: yes, 2010
Five times a day in the 83 square mile city of Cairo, over 30,000 muezzins call out the adhan, or call to prayer, calling believers to come and to pray.
Kipervaser, Anna, LLC, On Look Films
core  

The Limited Liability Company Experiment: Unlimited Flexibility, Uncertain Role [PDF]

open access: yes, 1995
Limited liability company (LLC) laws utilize provisions clearly of partnership origin in varying degrees.
Gazur, Wayne M.
core   +4 more sources

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

A stability improvement control strategy research for LLC resonant converter with single neuron PI-I double closed loop control

open access: yesAin Shams Engineering Journal
LLC resonant converters are widely used in the aerospace field. However, under traditional single-loop control, LLC resonant converters are prone to instability in the face of high-power load disturbances, which fails to meet the high stability ...
Zhangang Yang, Qingyu Zhou
doaj   +1 more source

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