Results 41 to 50 of about 27,877 (267)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Вестник Майкопского государственного технологического университета, 2023 Augmented reality (AR) and virtual reality (VR) are immersive technologies that allow users to get acquainted with digital content both in physical and virtual space, expanding the possibilities of the educational environment.The relevance of the ...
Anna Alexandrovna Paskova
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Proceedings of the International Conference on Automated Planning and Scheduling, 2013 In heuristic search and especially in optimal classical planning the computation of accurate heuristic values can take up the majority of runtime. In many cases, the heuristic computations for a search node and its successors are very similar, leading to significant duplication of effort.
Florian Pommerening, Malte Helmert
openaire +2 more sources
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Adaptive Array Beamforming Using a Combined LMS-LMS Algorithm [PDF]
IEEE Transactions on Antennas and Propagation, 2010 A new adaptive algorithm, called least mean square- least mean square (LLMS) algorithm, which employs an array image factor, , sandwiched in between two least mean square (LMS) algorithm sections, is proposed for different applications of array beamforming. It can operate with either prescribed or adaptive .
Srar, Jalal +2 more
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From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Proceedings of the Fourth Conference on Machine Translation (Volume 2: Shared Task Papers, Day 1), 2019 Two techniques provide the fabric of the Cambridge University Engineering Department's (CUED) entry to the WMT19 evaluation campaign: elastic weight consolidation (EWC) and different forms of language modelling (LMs). We report substantial gains by fine-tuning very strong baselines on former WMT test sets using a combination of checkpoint averaging and
Felix Stahlberg +3 more
openaire +2 more sources
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source