Results 111 to 120 of about 4,716 (190)

Role of Dmrt5 during development of midbrain dopaminergic progenitors

, 2011
This thesis investigates the previously un-described role of Dmrt5, a zinc-finger transcription factor, in ventral midbrain development. The spatio-temporal expression pattern of Dmrt5, described for the first time in this thesis, suggests that Dmrt5 may
Farley, Emma Kirsten, Farley, Emma Kirsten   +1 more
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Regenerative Medicine for the Aging Brain [PDF]

, 2014
In the central nervous system, cholinergic and dopaminergic (DA) neurons are among the cells most susceptible to the deleterious effects of age. Thus, the basal forebrain cholinergic system is known to undergo moderate neurodegenerative changes during ...
Goya, Rodolfo Gustavo, Hereñú, Claudia Beatriz, López León, Micaela, Reggiani, Paula Cecilia   +3 more
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Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling. [PDF]

, 2010
Topographic neuronal maps arise as a consequence of axon trajectory choice correlated with the localisation of neuronal soma, but the identity of the pathways coordinating these processes is unknown.
Kania, Artur, Kao, Tzu-Jen, Klar, Avihu, Laufer, Ed, Novitch, Bennett G, Okamoto, Hitoshi, Palmesino, Elena, Rousso, David L, Uemura, Osamu   +8 more
core   +4 more sources

Electron Microscopic and Immunohistochemical Findings of the Epidermal Basement Membrane in Two Families with Nail-patella Syndrome

Acta Dermato-Venereologica, 2019
Nail-patella syndrome is an autosomal dominant disorder characterized by nail dysplasia and skeletal anomaly. Some patients have been shown to have ultrastructural abnormalities of the glomerular basement membrane that result in nephrosis.
Satoru Shinkuma, Hideki Nakamura, Manami Maehara, Shota Takashima, Toshifumi Nomura, Yasuyuki Fujita, Satoshi Hasegawa, Kazuko C. Sato-Matsumura, Riichiro Abe, Hiroshi Shimizu   +9 more
doaj   +1 more source

Sejtbeültetés a központi idegszövetbe: a bevitt sejtek differenciációs állapota és a befogadó szövet harmonizációja = Implantation into the central nervous system: harmonisation of the implanted cells and the host tissue [PDF]

, 2007
A posztdoktori pályázat keretében végzett munkám során kerestem azokat a tényezőket, amelyek elősegíthetik a beültetett idegi őssejtek túlélését a kifejlett agyszövetbe. Az elért eredmények: 1.
Herberth, Balázs
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Noggin Over-Expressing Mouse Embryonic Fibroblasts and MS5 Stromal Cells Enhance Directed Differentiation of Dopaminergic Neurons from Human Embryonic Stem Cells.

PLoS ONE, 2015
Directed methods for differentiating human embryonic stem cells (hESCs) into dopaminergic (DA) precursor cells using stromal cells co-culture systems are already well established. However, not all of the hESCs differentiate into DA precursors using these
Mi-Sun Lim, Min-Seop Shin, Soo Young Lee, Yang-Ki Minn, Jeong-Kyu Hoh, Youl-Hee Cho, Dong-Wook Kim, Sang-Hun Lee, Chun-Hyung Kim, Chang-Hwan Park   +9 more
doaj   +1 more source

Electroacupuncture alleviates inflammatory pain via the activation of GABAergic inhibitory interneurons in mouse spinal dorsal horn

Brain Research Bulletin
Electroacupuncture (EA), a modern adaptation of traditional acupuncture, has shown promising analgesic effects across various pain models. However, the underlying central mechanisms remain insufficiently characterized.
Jiawei Zhang, Yang Bao, Mengye Zhu, Quan Wan, Jinjin Zhang, Xuezhong Cao, Huan Zou, Qinghua Yin, Ziming Chen, Gang Xu, Xuexue Zhang, Daying Zhang, Tao Liu, Yong Zhang   +13 more
doaj   +1 more source

Progress in Pathogenesis of Proteinuria

International Journal of Nephrology, 2012
Aims. Proteinuria not only is a sign of kidney damage, but also is involved in the progression of renal diseases as an independent pathologic factor. Clinically, glomerular proteinuria is most commonly observed, which relates to structural and functional
Aihua Zhang, Songming Huang
doaj   +1 more source

Non-dialyzable uremic toxins and renal tubular cell damage in CKD patients: a systems biology approach

European Journal of Medical Research
Background Chronic kidney disease presents global health challenges, with hemodialysis as a common treatment. However, non-dialyzable uremic toxins demand further investigation for new therapeutic approaches.
Roya Asadi, Pejman Shadpour, Akram Nakhaei   +2 more
doaj   +1 more source

Wide spectrum of NR5A1-related phenotypes in 46,XY and 46,XX individuals [PDF]

, 2016
Steroidogenic factor 1 (NR5A1, SF-1, Ad4BP) is a transcriptional regulator of genes involved in adrenal and gonadal development and function. Mutations in NR5A1 have been among the most frequently identified genetic causes of gonadal development ...
Achermann, JC, Correa, RV, da Silva, TE, Domenice, S, Ferraz-de-Souza, B, Ferreira, FM, Frade Costa, EM, Gomes, NL, Lerario, AM, Lin, L, Machado, AZ, Mendonca, BB, Montenegro, LR, Narciso, A, Nishi, MY, Silva, RB   +15 more
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